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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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USP9Y

ubiquitin specific peptidase 9, Y-linked

May function as a ubiquitin-protein or polyubiquitin hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important role regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade. Deubiqitination of SMAD4 by USP9X re-empowers its competence to mediate TGF-beta signaling.

Gene Name: ubiquitin specific peptidase 9, Y-linked
Family/Subfamily: Protease , Cysteine C19
Synonyms: USP9Y, DFFRY, Deubiquitinating enzyme FAF-Y, Ubiquitin thiolesterase FAF-Y, SPGFY2, Ubiquitin thioesterase FAF-Y
Target Sequences: NM_004654 NP_004645.2 O00507

Filtered By: None
Target
USP9Y (5)
Reactivity
Human (5)
Application
WB (5)
ELISA (1)
Host
rabbit (4)
mouse (1)
Isotype
IgG2a,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (4)
Clone
2D3 (1)
Format
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (2)
Epitope
C-Terminus (4)
Publications
No (5)
Showing 1-5 of 5 results

USP9Y Antibody (clone 2D3) LS-C198543
Mouse Monoclonal [clone 2D3] (IgG2a,k) to Human USP9Y
Human
ELISA WB
Unconjugated
100µg  $355.00
Detection limit for recombinant GST tagged USP9Y is approximately 1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged USP9Y is approximately 1 ng/ml as a capture antibody.

USP9Y Antibody (C-Terminus) LS-C116831
Rabbit Polyclonal to Human USP9Y
Human
WB
Unconjugated
50µg  $365.00
USP9Y antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
USP9Y antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

USP9Y Antibody (C-Terminus, HRP) LS-C465768
Rabbit Polyclonal to Human USP9Y
Human
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
USP9Y antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
USP9Y antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

USP9Y Antibody (C-Terminus, Biotin) LS-C466147
Rabbit Polyclonal to Human USP9Y
Human
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
USP9Y antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
USP9Y antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

USP9Y Antibody (C-Terminus, FITC) LS-C466148
Rabbit Polyclonal to Human USP9Y
Human
WB
FITC Conjugated
100µl 1mg/ml  $385.00
USP9Y antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
USP9Y antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-5 of 5 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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