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USP37

ubiquitin specific peptidase 37

Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2).

Gene Name: ubiquitin specific peptidase 37
Synonyms: USP37, KIAA1594, Ubiquitin specific protease 37, Ubiquitin thiolesterase 37, Deubiquitinating enzyme 37, Tmp_locus_50, Ubiquitin thioesterase 37
Target Sequences: Q86T82 Q86T82

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Products
Antibodies (25)
Primary (25)
USP37 (25)
Human (25)
Mouse (4)
Rat (5)
Bovine (3)
Chicken (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Hamster (3)
Horse (3)
Monkey (3)
Pig (3)
Xenopus (3)
Zebrafish (3)
IHC (7)
IHC-P (1)
WB (18)
ELISA (12)
IP (3)
Peptide-ELISA (1)
rabbit (25)
IgG (17)
polyclonal pc (25)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (14)
aa67-94 (7)
aa791-840 (4)
aa2-217 (2)
aa930-C-term (2)
aa125-175 (1)
No (25)
USP37 Antibody
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USP37 Rabbit anti-Human Polyclonal (aa2-217) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
USP37 Antibody - Immunohistochemistry image at a dilution of 1:200 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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USP37 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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USP37 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
USP37 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
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USP37 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
USP37 Antibody - Detection of Human USP37 by Immunohistochemistry. Sample: FFPE section of human non-small cell lung cancer. Antibody: Affinity purified rabbit anti-USP37 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
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USP37 Rabbit anti-Human Polyclonal (aa930-C-term) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
USP37 Antibody - 1:100 staining rat brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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USP37 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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USP37 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$341
USP37 Antibody - Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue  using USP37 Polyclonal Antibody at dilution of 1:45(×200)
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USP37 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
USP37 Antibody - Detection of Human USP37 by Immunohistochemistry. Sample: FFPE section of human non-small cell lung cancer. Antibody: Affinity purified rabbit anti-USP37 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
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USP37 Rabbit anti-Human Polyclonal (aa125-175) Antibody
Human
IHC, IP
Unconjugated
10 µg/$295; 100 µl/$514
Select
USP37 Rabbit anti-Human Polyclonal (aa67-94) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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USP37 Rabbit anti-Human Polyclonal (aa67-94) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
USP37 Rabbit anti-Human Polyclonal (aa67-94) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
USP37 Rabbit anti-Human Polyclonal (aa67-94) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
USP37 Rabbit anti-Human Polyclonal (aa67-94) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
USP37 Rabbit anti-Human Polyclonal (aa67-94) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
USP37 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
USP37 Antibody
Select
USP37 Rabbit anti-Human Polyclonal (aa2-217) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$332
USP37 Antibody - Detection of Human USP37 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-USP37 used at a dilution of 1:250. Epitope Retrieval Buffer-High pH (IHC-101J) was substituted for Epitope Retrieval Buffer-Reduced pH.
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USP37 Rabbit anti-Human Polyclonal (aa930-C-term) Antibody
Human
IHC
Unconjugated
2 µg/$295; 100 µl/$532
USP37 Antibody - USP37 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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USP37 Rabbit anti-Human Polyclonal (aa791-840) Antibody
Human
WB
Unconjugated
100 µl/$424
USP37 Antibody - USP37 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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USP37 Rabbit anti-Human Polyclonal (aa791-840) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bovine, Mouse, Dog, Guinea pig, Rat, Hamster, Human, Monkey, Chimpanzee, Gibbon
WB
HRP Conjugated
100 µl/$469
USP37 Antibody - USP37 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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USP37 Rabbit anti-Human Polyclonal (aa791-840) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bovine, Mouse, Dog, Guinea pig, Rat, Hamster, Human, Monkey, Chimpanzee, Gibbon
WB
Biotin Conjugated
100 µl/$469
USP37 Antibody - USP37 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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USP37 Rabbit anti-Human Polyclonal (aa791-840) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bovine, Mouse, Dog, Guinea pig, Rat, Hamster, Human, Monkey, Chimpanzee, Gibbon
WB
FITC Conjugated
100 µl/$469
USP37 Antibody - UBP37 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The UBP37 antibody detected the UBP37 protein (arrow).
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USP37 Rabbit anti-Human Polyclonal (aa67-94) Antibody
Human
WB
Unconjugated
400 µl/$393
USP37 Antibody - Western blot analysis of extracts of various cell lines using USP37 Polyclonal Antibody at dilution of 1:2000.
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USP37 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).