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USP30

ubiquitin specific peptidase 30

Deubiquitinating enzyme that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PARK2): hydrolyzes ubiquitin attached by parkin on target proteins, such as RHOT1/MIRO1 and TOMM20, thereby blocking parkin's ability to drive mitophagy (PubMed:24896179). Acts as negative regulator of mitochondrial fusion by mediating deubiquitination of MFN1 and MFN2.

Gene Name: ubiquitin specific peptidase 30
Synonyms: USP30, Ubiquitin thiolesterase 30, Ubiquitin specific protease 30, Deubiquitinating enzyme 30, Ub-specific protease 30, Ubiquitin thioesterase 30, Ubiquitin-specific protease 30
Target Sequences: NM_032663 AAH04868.1 Q70CQ3

☰ Filters
Antibodies (23)
Proteins (4)
Over-Expression Lysate (2)
Primary (23)
Recombinant (2)
USP30 (27)
Human (23)
Mouse (13)
Rat (9)
Bat (3)
Bovine (3)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (4)
Rabbit (3)
IHC (4)
IHC-P (2)
WB (20)
ELISA (13)
ICC (1)
IF (3)
Peptide-ELISA (2)
rabbit (23)
IgG (17)
polyclonal pc (23)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Preservative Free (1)
Unconjugated (12)
aa156-185 (7)
aa141-190 (4)
C-Terminus (3)
1-80 aa, N-terminal (1)
N-Terminus (1)
aa101-400 (1)
aa31-80 (1)
No (27)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
USP30 Antibody - Immunofluorescent analysis of USP30 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
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USP30 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Dog, Rat, Human, Monkey
ICC, IF, WB
Unconjugated
100 µl/$299
USP30 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer using antibody at dilution of 1:100.
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USP30 Rabbit anti-Human Polyclonal (aa101-400) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
USP30 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
USP30 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
USP30 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
USP30 Antibody - Human Breast, Ducts: Formalin-Fixed, Paraffin-Embedded (FFPE)
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USP30 Rabbit anti-Human Polyclonal (aa141-190) Antibody
Human
IHC-P, WB
Unconjugated
100 µl/$424
USP30 Antibody - USP30 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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USP30 Rabbit anti-Human Polyclonal (aa141-190) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
USP30 Antibody - USP30 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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USP30 Rabbit anti-Human Polyclonal (aa141-190) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
USP30 Antibody - USP30 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
USP30 Rabbit anti-Human Polyclonal (aa141-190) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
USP30 Antibody - Western blot of USP30 antibody
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USP30 Rabbit anti-Human Polyclonal (1-80 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
USP30 Antibody - Western blot analysis of lysates from HeLa cells, using USP30 Antibody. The lane on the right is blocked with the synthesized peptide.
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USP30 Rabbit anti-Human Polyclonal (aa31-80) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
USP30 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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USP30 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
USP30 Rabbit anti-Human Polyclonal (aa156-185) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
USP30 Rabbit anti-Human Polyclonal (aa156-185) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
USP30 Rabbit anti-Human Polyclonal (aa156-185) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
USP30 Rabbit anti-Human Polyclonal (aa156-185) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
USP30 Rabbit anti-Human Polyclonal (aa156-185) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
USP30 Rabbit anti-Human Polyclonal (aa156-185) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
USP30 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
USP30 Antibody - Immunofluorescence analysis of NIH/3T3 cells using USP30 Polyclonal Antibody at dilution of 1:100 (40x lens).Blue: DAPI for nuclear staining.
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USP30 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
USP30 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
USP30 Antibody - USP30 Antibody western blot of A549 cell line lysates (35 ug/lane). The USP30 antibody detected the USP30 protein (arrow).
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USP30 Rabbit anti-Human Polyclonal (aa156-185) Antibody
Human
WB
Unconjugated
400 µl/$393
USP30 Antibody - Western blot analysis of extracts of various cell lines, using USP30 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
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USP30 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
USP30 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
58.3 kDa
100 µg/$494
USP30 Protein - 12.5% SDS-PAGE of human USP30 stained with Coomassie Blue
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Wheat Germ Extract
GST
81.62 kDa
2 µg/$439
Viewing 1-25 of 27 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).