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USP21

ubiquitin specific peptidase 21

Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination (By similarity). Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates.

Gene Name: ubiquitin specific peptidase 21
Family/Subfamily: Protease , Cysteine C19
Synonyms: USP21, Deubiquitinating enzyme 21, Ubiquitin thioesterase 21, Ubiquitin-specific protease 16, USP23, NEDD8-specific protease, Ubiquitin specific protease 21, Ubiquitin thiolesterase 21
Target Sequences: NM_012475 CAH72142.1 Q9UK80

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Products
Proteins (7)
Over-Expression Lysate (4)
Recombinant (3)
USP21 (7)
No (7)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (5)
Human (5)
293T Cells (2)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (1)
USP21 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
62.5 kDa
100 µg/$710
USP21 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
62.5 kDa
100 µg/$494
USP21 Protein - 12.5% SDS-PAGE of human USP21 stained with Coomassie Blue
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Wheat Germ Extract
GST
89 kDa
2 µg/$439
USP21 Protein - Purified recombinant protein USP21 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
62.5 kDa
20 µg/$1,107
USP21 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
USP21 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
62.5 kDa
20 µg/$150
USP21 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
62.5 kDa
20 µg/$215
Viewing 1-7 of 7 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).