USP16

ubiquitin specific peptidase 16

Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.

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Products

Proteins (8)

Type

Over-Expression Lysate (6)

Recombinant (2)

Target

USP16 (8)

Publications

No (8)

Tag

GST (1)

Myc-DDK (Flag) (7)

Species

Human (5)

Source

293T Cells (3)

HEK 293 Cells (4)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human USP16 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84437

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

93.3 kDa

Price:

20 µg/$150

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Human USP16 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84438

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

93.4 kDa

Price:

20 µg/$215

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Human USP16 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84440

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

93.4 kDa

Price:

20 µg/$150

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Human USP16 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69366

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

93.4 kDa

Price:

20 µg/$1,107

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Human USP16 Protein (Recombinant GST) (Full Length) - LS-G32245

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

119.8 kDa

Price:

10 µg/$479; 25 µg/$670

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USP16 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122779

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

93.3 kDa

Price:

100 µg/$494

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USP16 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115296

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

93.4 kDa

Price:

100 µg/$494

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USP16 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120876

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

93.4 kDa

Price:

100 µg/$710

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