USP15

ubiquitin specific peptidase 15

Hydrolase that removes conjugated ubiquitin from target proteins and regulates various pathways such as the TGF-beta receptor signaling and NF-kappa-B pathways. Acts as a key regulator of TGF-beta receptor signaling pathway, but the precise mechanism is still unclear: according to a report, acts by promoting deubiquitination of monoubiquitinated R-SMADs (SMAD1, SMAD2 and/or SMAD3), thereby alleviating inhibition of R-SMADs and promoting activation of TGF-beta target genes (PubMed:21947082). According to another reports, regulates the TGF-beta receptor signaling pathway by mediating deubiquitination and stabilization of TGFBR1, leading to an enhanced TGF-beta signal (PubMed:22344298). Able to mediate deubiquitination of monoubiquitinated substrates as well as 'Lys-48'-linked polyubiquitin chains, protecting them against proteasomal degradation. Acts as an associated component of COP9 signalosome complex (CSN) and regulates different pathways via this association: regulates NF-kappa-B by mediating deubiquitination of NFKBIA and deubiquitinates substrates bound to VCP. Protects APC and human papillomavirus type 16 protein E6 against degradation via the ubiquitin proteasome pathway.

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Products

Antibodies (33)

Proteins (5)

Type

Over-Expression Lysate (2)

Primary (33)

Recombinant (3)

Target

USP15 (38)

Reactivity

Human (33)

Mouse (26)

Rat (10)

Bat (3)

Bovine (5)

Chicken (2)

Chimpanzee (3)

Dog (4)

Gibbon (3)

Guinea pig (3)

Hamster (1)

Horse (4)

Monkey (4)

Pig (3)

Rabbit (4)

Xenopus (4)

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Application

IHC (7)

IHC-P (5)

WB (28)

ELISA (17)

ICC (1)

IF (2)

IP (1)

Peptide-ELISA (3)

Host

rabbit (32)

goat (1)

Product Group

IHCPlus (2)

Isotype

IgG (24)

Clonality

polyclonal pc (33)

Format

APC Conjugated (2)

Azide-free (2)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (20)

Epitope

aa151-180 (7)

aa254-282 (7)

aa691-740 (4)

aa960-C-term (2)

50-130 aa, N-terminal (1)

aa48-255 (1)

aa68-117 (1)

aa920-981 (1)

aa970-981 (1)

Publications

No (38)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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IHC-plus™ USP15 Antibody (aa970-981) LS-B6452

(4.0) Rating

Antibody:

USP15 Goat anti-Human Polyclonal (aa970-981) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Rabbit, Dog, Hamster, Horse, Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µg/$485

Select

IHC-plus™ USP15 Antibody (aa960-C-term) LS-B14420

(4.0) Rating

Antibody:

USP15 Rabbit anti-Human Polyclonal (aa960-C-term) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

USP15 Antibody (aa48-255) LS-C178691

Antibody:

USP15 Rabbit anti-Human Polyclonal (aa48-255) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$332

Select

USP15 Antibody (50-130 aa, N-terminal) LS-C386602

Antibody:

USP15 Rabbit anti-Human Polyclonal (50-130 aa, N-terminal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

USP15 Antibody (aa151-180) LS-C329056

Antibody:

USP15 Rabbit anti-Human Polyclonal (aa151-180) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

USP15 Antibody (aa151-180, Biotin) LS-C284179

Antibody:

USP15 Rabbit anti-Human Polyclonal (aa151-180) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

USP15 Antibody (aa151-180, FITC) LS-C284180

Antibody:

USP15 Rabbit anti-Human Polyclonal (aa151-180) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

USP15 Antibody (aa151-180, APC) LS-C284178

Antibody:

USP15 Rabbit anti-Human Polyclonal (aa151-180) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

USP15 Antibody (aa151-180, PE) LS-C284181

Antibody:

USP15 Rabbit anti-Human Polyclonal (aa151-180) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

USP15 Antibody (aa151-180, Azide-free, HRP) LS-C284182

Antibody:

USP15 Rabbit anti-Human Polyclonal (aa151-180) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

USP15 Antibody (aa254-282) LS-C326227

Antibody:

USP15 Rabbit anti-Human Polyclonal (aa254-282) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

USP15 Antibody (aa254-282, Biotin) LS-C273171

Antibody:

USP15 Rabbit anti-Human Polyclonal (aa254-282) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

USP15 Antibody (aa254-282, FITC) LS-C273172

Antibody:

USP15 Rabbit anti-Human Polyclonal (aa254-282) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

USP15 Antibody (aa254-282, APC) LS-C273170

Antibody:

USP15 Rabbit anti-Human Polyclonal (aa254-282) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

USP15 Antibody (aa254-282, Azide-free, HRP) LS-C273173

Antibody:

USP15 Rabbit anti-Human Polyclonal (aa254-282) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

USP15 Antibody (aa254-282, PE) LS-C273175

Antibody:

USP15 Rabbit anti-Human Polyclonal (aa254-282) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

USP15 Antibody (aa920-981) LS-C185639

Antibody:

USP15 Rabbit anti-Human Polyclonal (aa920-981) Antibody

Reactivity:

Chicken, Bovine, Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

Select

USP15 Antibody LS-C676690

Antibody:

USP15 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

USP15 Antibody LS-C805488

Antibody:

USP15 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

USP15 Antibody LS-C409033

Antibody:

USP15 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

USP15 Antibody LS-C742741

Antibody:

USP15 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

USP15 Antibody LS-C824717

Antibody:

USP15 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

USP15 Antibody (aa960-C-term) LS-C286720

Antibody:

USP15 Rabbit anti-Human Polyclonal (aa960-C-term) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

1 µg/$295; 100 µl/$532

Select

USP15 Antibody (aa68-117) LS-C200807

Antibody:

USP15 Rabbit anti-Human Polyclonal (aa68-117) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

USP15 Antibody LS-C834373

Antibody:

USP15 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Viewing 1-25 of 38 product results

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