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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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USP14

ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)

Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).

Gene Name: ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
Family/Subfamily: Protease , Cysteine C19
Synonyms: USP14, Deubiquitinating enzyme 14, Ubiquitin thioesterase 14, Ubiquitin thiolesterase 14, TGT, TRNA-guanine transglycosylase, Ubiquitin specific protease 14
Target Sequences: NM_005151 NP_005142.1 P54578


USP14 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human USP14
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50µl   1mg/ml   $425.00
Select
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, Flo, IF, WB
Unconjugated
100µg   $435.00
USP14 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Select
Rabbit Polyclonal to Human USP14
Human
IHC, IHC-P, WB
Unconjugated
400µl   $325.00
USP14 Antibody - Detection of Human USP14 by Immunohistochemistry : Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human USP14
Human
IHC, IHC-P, IP, WB
Unconjugated
100µl   1mg/ml   $405.00
USP14 Antibody - USP14 monoclonal antibody (M08), clone 1F8. Western blot of USP14 expression in PC-12.
Select
Mouse Monoclonal [clone 1F8] (IgG2a,k) to Human USP14
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µg   $365.00
Select
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, IHC, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, IHC, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, IHC, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, IHC, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, IHC, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, IHC, WB
PE Conjugated
200µl   $740.00
USP14 Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue using USP14 Antibody at dilution of 1:100
Select
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, WB
Unconjugated
50µg   $285.00; 100µg   $385.00
USP14 Antibody - Western blot of Ubiquitin carboxyl-terminal hydrolase 14 antibody at 2 ug/ml lane 1: HeLa whole cell lysate lane 2: 293T whole cell lysate Lane 3: NIH3T3 whole cell lysate Secondary: Goat polyclonal to Rabbit IgG at 1:10000 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, WB
FITC Conjugated
50µg   $285.00; 100µg   $385.00
USP14 Antibody - Immunohistochemistry of USP14 antibody
Select
Rabbit Polyclonal to Human USP14
Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $265.00
Select
Rabbit Polyclonal to Human USP14
Rabbit, Mouse, Human
ELISA, WB
Unconjugated
100µg   $305.00
Select
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human USP14
Human
ELISA, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal to Human USP14
Mouse, Human
ELISA, WB
Unconjugated
100µg   100µl   1mg/ml   $305.00
USP14 Antibody - Western blot analysis USP14 using Jurkat whole cells lysates
Select
Rabbit Polyclonal (IgG) to Human USP14
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
Viewing 1-25 of 39 products



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).