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USB1

U6 snRNA biogenesis 1

USB1 is a protein with several conserved domains, however, its exact function is not known. Mutations in this gene are associated with poikiloderma with neutropenia (PN), which shows phenotypic overlap with Rothmund-Thomson syndrome (RTS) caused by mutations in the RECQL4 gene. It is believed that this gene product interacts with RECQL4 protein via SMAD4 proteins, explaining the partial clinical overlap between PN and RTS. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene Name: U6 snRNA biogenesis 1
Synonyms: USB1, C16orf57, Mpn1, UPF0406 protein C16orf57, U six biogenesis 1, PN, HUsb1, HVSL motif containing 1, HVSL1, U6 snRNA biogenesis 1
Target Sequences: NM_024598 NP_078874.2 Q9BQ65

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Products
Antibodies (15)
Primary (15)
USB1 (15)
Human (15)
Mouse (4)
Rat (3)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Hamster (4)
Horse (4)
Monkey (4)
Pig (3)
Rabbit (3)
IHC (1)
IHC-P (1)
WB (11)
ELISA (4)
Peptide-ELISA (1)
rabbit (9)
mouse (5)
goat (1)
IgG (6)
IgG2a (2)
IgG2b (2)
monoclonal mc (4)
polyclonal pc (11)
OTI1B1 (2)
OTI4B1 (2)
Biotin Conjugated (2)
Carrier-free (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (9)
aa150-199 (4)
aa1-265 (1)
aa1-266 (1)
aa154-167 (1)
No (15)
USB1 Antibody - Western blot analysis of extracts of various cell lines, using USB1 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 180s.
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USB1 Rabbit anti-Human Polyclonal (aa1-265) Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
USB1 Antibody - Immunohistochemistry Dilution at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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USB1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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USB1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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USB1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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USB1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
USB1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY C16orf57. (Right lane) cDNA for 48 hrs and lysed
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USB1 Mouse anti-Human Monoclonal (OTI1B1) Antibody
Human
WB
Unconjugated
100 µl/$434
USB1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY C16orf57. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C16orf57. (1:2000)
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USB1 Mouse anti-Human Monoclonal (Carrier-free) (OTI1B1) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
USB1 Antibody - C16orf57 antibody (0.3 ug/ml) staining of Human Skin lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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USB1 Goat anti-Human Polyclonal (aa154-167) Antibody
Hamster, Horse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
USB1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY C16orf57. (Right lane) cDNA for 48 hrs and lysed
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USB1 Mouse anti-Human Monoclonal (OTI4B1) Antibody
Human
WB
Unconjugated
100 µl/$434
USB1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY C16orf57. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C16orf57. (1:2000)
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USB1 Mouse anti-Human Monoclonal (Carrier-free) (OTI4B1) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
USB1 Antibody - C16orf57 antibody Western blot of PANC1 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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USB1 Rabbit anti-Human Polyclonal (aa150-199) Antibody
Human
WB
Unconjugated
100 µl/$424
USB1 Antibody - C16orf57 antibody Western blot of PANC1 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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USB1 Rabbit anti-Human Polyclonal (aa150-199) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
USB1 Antibody - C16orf57 antibody Western blot of PANC1 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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USB1 Rabbit anti-Human Polyclonal (aa150-199) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
USB1 Antibody - C16orf57 antibody Western blot of PANC1 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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USB1 Rabbit anti-Human Polyclonal (aa150-199) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
Select
USB1 Mouse anti-Human Polyclonal (aa1-266) Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-15 of 15 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).