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UROS

uroporphyrinogen III synthase

Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme).

Gene Name: uroporphyrinogen III synthase
Synonyms: UROS, Hydroxymethylbilane hydrolyase, UROIIIS, Uroporphyrinogen-III synthase, Uroporphyrinogen III synthase
Target Sequences: NM_000375 NP_000366.1 P10746

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).