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UPK1A / Uroplakin 1A

uroplakin 1A

UPK1A / Uroplakin 1A is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Alternative splicing results in multiple transcript variants of this gene.

Gene Name: uroplakin 1A
Family/Subfamily: Tetraspan , not assigned-Tetraspan
Synonyms: UPK1A, UP1A, UPIA, Uroplakin-1a, Tetraspanin-21, Tspan-21, TSPAN21, UPKA, Uroplakin 1A, Uroplakin Ia
Target Sequences: NM_007000 NP_008931.1 O00322

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
UPK1A / Uroplakin 1A (4)
No (4)
His, N-Terminal (1)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (2)
Mouse (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
UPK1A / Uroplakin 1A Protein - Recombinant Uroplakin 1A By SDS-PAGE
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E. coli
His, N-Terminal
17.1 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
UPK1A / Uroplakin 1A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
28.7 kDa
100 µg/$494
UPK1A / Uroplakin 1A Protein - Recombinant Uroplakin 1A By SDS-PAGE
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E. coli
His-T7
17.0 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
UPK1A / Uroplakin 1A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
28.7 kDa
20 µg/$150
Viewing 1-4 of 4 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).