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UPF3B

UPF3 regulator of nonsense transcripts homolog B (yeast)

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene.

Gene Name: UPF3 regulator of nonsense transcripts homolog B (yeast)
Synonyms: UPF3B, HUPF3B, MRXS14, HUpf3p-X, RENT3B, UPF3X
Target Sequences: NM_023010 NP_075386.1 Q9BZI7

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Products
Antibodies (17)
Primary (17)
UPF3B (17)
Human (17)
Mouse (3)
Rat (2)
Bovine (3)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Horse (1)
Monkey (3)
Pig (1)
Rabbit (4)
Sheep (1)
IHC (8)
IHC-P (8)
WB (12)
ELISA (4)
IF (1)
IP (2)
rabbit (17)
Product Group
IHCPlus (1)
IgG (16)
polyclonal pc (17)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (8)
N-Terminus (4)
aa252-301 (4)
aa300-350 (1)
aa416-452 (1)
aa433-483 (1)
No (17)
UPF3B Antibody - UPF3B antibody ARP40998_T100-NP_075386-UPF3B (UPF3 regulator of nonsense transcripts homolog B (yeast)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human stomach.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UPF3B Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
UPF3B Antibody - UPF3B antibody ARP40998_T100-NP_075386-UPF3B (UPF3 regulator of nonsense transcripts homolog B (yeast)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human stomach.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UPF3B Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Bovine, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
UPF3B Antibody - UPF3B antibody ARP40998_T100-NP_075386-UPF3B (UPF3 regulator of nonsense transcripts homolog B (yeast)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human stomach.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UPF3B Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Bovine, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
UPF3B Antibody - UPF3B antibody ARP40998_T100-NP_075386-UPF3B (UPF3 regulator of nonsense transcripts homolog B (yeast)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human stomach.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UPF3B Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Bovine, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
UPF3B Antibody - Immunohistochemistry Dilution at 1:500 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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UPF3B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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UPF3B Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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UPF3B Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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UPF3B Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
UPF3B Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
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UPF3B Rabbit anti-Human Polyclonal (aa433-483) Antibody
Human
IHC, IHC-P, IP
Unconjugated
50 µl/$460
UPF3B Antibody - UPF3B/RENT3B antibody IHC-paraffin. IHC(P): Mouse Testis Tissue.
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UPF3B Rabbit anti-Human Polyclonal (aa416-452) Antibody
Rabbit, Mouse, Dog, Sheep, Rat, Pig, Horse, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
UPF3B Antibody
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UPF3B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
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UPF3B Rabbit anti-Human Polyclonal (aa300-350) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
UPF3B Antibody - UPF3B antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UPF3B Rabbit anti-Human Polyclonal (aa252-301) Antibody
Human
WB
Unconjugated
100 µl/$424
UPF3B Antibody - UPF3B antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UPF3B Rabbit anti-Human Polyclonal (aa252-301) (HRP) Antibody
Rabbit, Dog, Human, Monkey, Chimpanzee, Gibbon
WB
HRP Conjugated
100 µl/$469
UPF3B Antibody - UPF3B antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UPF3B Rabbit anti-Human Polyclonal (aa252-301) (Biotin) Antibody
Rabbit, Dog, Human, Monkey, Chimpanzee, Gibbon
WB
Biotin Conjugated
100 µl/$469
UPF3B Antibody - UPF3B antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UPF3B Rabbit anti-Human Polyclonal (aa252-301) (FITC) Antibody
Rabbit, Dog, Human, Monkey, Chimpanzee, Gibbon
WB
FITC Conjugated
100 µl/$469
UPF3B Antibody - Western blot analysis of extracts of various cell lines, using UPF3B antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
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UPF3B Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Viewing 1-17 of 17 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).