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UP / UPP1

uridine phosphorylase 1

The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP; EC 2.4.2.3) and thymidine phosphorylase (TP; EC 2.4.2.4), in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate. Pyrimidine nucleoside phosphorylases can add ribose or deoxyribose to pyrimidine bases to form nucleosides that can be incorporated into RNA or DNA (Watanabe and Uchida, 1995 [PubMed 7488099]).

Gene Name:	uridine phosphorylase 1
Synonyms:	UPP1, UPASE, Uridine phosphorylase, Uridine phosphorylase 1, UPase 1, UPP, UrdPase 1, UDRPASE, UP
Target Sequences:	NM_003364 NP_003355.1 Q16831

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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