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UNG / Uracil DNA Glycosylase

uracil-DNA glycosylase

UNG / Uracil DNA Glycosylase is one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.

Gene Name: uracil-DNA glycosylase
Synonyms: UNG, DGU, HIGM4, HIGM5, Uracil-DNA glycosylase, UNG1, UNG2, UDG, UNG15
Target Sequences: NM_003362 NP_003353.1 P13051

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Proteins (11)
Over-Expression Lysate (4)
Recombinant (7)
UNG / Uracil DNA Glycosylase (11)
No (11)
GST (1)
GST, N-terminus (2)
His (1)
His, N-Terminal (2)
Myc-DDK (Flag) (5)
E. coli (1)
Human (8)
293T Cells (2)
E. coli (4)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (3)
UNG / Uracil DNA Glycosylase Protein - Recombinant  Uracil DNA Glycosylase By SDS-PAGE
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E. coli
His, N-Terminal
38.3 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
UNG / Uracil DNA Glycosylase Protein
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E. coli
His, N-Terminal
33.9 kDA
50 µg/$419
UNG / Uracil DNA Glycosylase Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
UNG / Uracil DNA Glycosylase Protein - Purified recombinant protein UNG was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
34.5 kDa
20 µg/$1,107
UNG / Uracil DNA Glycosylase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
33.92 kDa
20 µg/$150
UNG / Uracil DNA Glycosylase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
34.5 kDa
20 µg/$150
UNG / Uracil DNA Glycosylase Protein - 12.5% SDS-PAGE of human UNG stained with Coomassie Blue
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Wheat Germ Extract
GST
60.3 kDa
2 µg/$439
UNG / Uracil DNA Glycosylase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
34.5 kDa
100 µg/$494
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E. coli
GST, N-terminus
52 kDa
100 µg/$843
UNG / Uracil DNA Glycosylase Protein
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E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
UNG / Uracil DNA Glycosylase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
33.92 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).