UNC45B

unc-45 homolog B (C. elegans)

UNC45B is a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

UNC45B (4)

Publications

No (4)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human UNC45B Protein (Recombinant GST) (Full Length) - LS-G36669

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

121.2 kDa

Price:

2 µg/$439

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Human UNC45B Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72961

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

103.6 kDa

Price:

20 µg/$1,107

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Human UNC45B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G94047

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

103.6 kDa

Price:

20 µg/$215

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UNC45B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102430

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

103.6 kDa

Price:

100 µg/$710

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