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UNC119 / Retinal Protein 4
unc-119 homolog (C. elegans)
Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid-binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Probably plays a role in trafficking proteins in photoreceptor cells. Plays important roles in mediating Src family kinase signals for the completion of cytokinesis via RAB11A.
| Gene Name: | unc-119 homolog (C. elegans) |
| Synonyms: | UNC119, POC7A, Protein unc-119 homolog A, RG4, Unc-119 homolog (C. elegans), Unc119 (C.elegans) homolog, POC7, Retinal protein 4, HRG4 |
| Target Sequences: | NM_005148 NP_005139.1 Q13432 |
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