UMPS / OPRT

uridine monophosphate synthetase

UMPS / OPRT encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

UMPS / OPRT (8)

Publications

No (8)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His-T7 (2)

Myc-DDK (Flag) (3)

Species

Human (6)

Mouse (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human UMPS / OPRT Protein (Recombinant GST, N-terminus) (aa381-479) - LS-G60486

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human UMPS / OPRT Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66493

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52 kDa

Price:

20 µg/$1,107

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Human UMPS / OPRT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77833

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52 kDa

Price:

20 µg/$150

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Human UMPS / OPRT Protein (Recombinant His-T7) (aa205-480) - LS-G24978

Source:

E. coli

Tag:

His-T7

Molecular Weight:

33.7 kDa

Price:

10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934

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Mouse UMPS / OPRT Protein (Recombinant His-T7) (aa311-481) - LS-G24979

Source:

E. coli

Tag:

His-T7

Molecular Weight:

22.0 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Human UMPS / OPRT Protein (Recombinant GST) (Full Length) - LS-G30844

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

78.6 kDa

Price:

10 µg/$479; 25 µg/$670

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UMPS / OPRT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123227

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52 kDa

Price:

100 µg/$494

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Human UMPS / OPRT Protein (Recombinant His) - LS-G2004

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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