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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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UMOD / Uromodulin

uromodulin

UMOD / Uromodulin is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants.

Gene Name: uromodulin
Synonyms: UMOD, ADMCKD2, FJHN, HNFJ, MCKD2, THGP, THP, Uromucoid, Tamm-Horsfall glycoprotein, HNFJ1, Uromodulin
Target Sequences: NM_003361 NP_003352.2 P07911

Publications (3)

1
Extracellular vesicles in urine of women with but not without kidney stones manifest patterns similar to men: a case control study. Jayachandran M, Lugo G, Heiling H, Miller VM, Rule AD, Lieske JC. Biology of sex differences. 2015 6:2. (Flo; Human) [Full Text Article] [PubMed:25729563] [PMC:PMC4345020] Related Antibodies: LS-B3105.
2
Specific renal parenchymal-derived urinary extracellular vesicles identify age-associated structural changes in living donor kidneys. Turco AE, Lam W, Rule AD, Denic A, Lieske JC, Miller VM, Larson JJ, Kremers WK, Jayachandran M. Journal of Extracellular Vesicles. 2016 5:29642. (Flo; Human) [PubMed:26837814] [PMC:PMC4737715] Related Antibodies: LS-B3105.
3
Novel fixed z-direction (FiZD) kidney primordia and an organoid culture system for time-lapse confocal imaging. Saarela U, Akram SU, Desgrange A, Rak-Raszewska A, Shan J, Cereghini S, Ronkainen VP, Heikkilä J, Skovorodkin I, Vainio SJ. Development (Cambridge, England). 2017 144:1113-1117. (IHC; Mouse) [Full Text Article] [PubMed:28219945] [PMC:PMC5358112]

Filtered By: None
Target
UMOD / Uromodulin (77)
Reactivity
Human (46)
Mouse (14)
Rat (11)
Bovine (4)
Chimpanzee (6)
Dog (15)
Gibbon (3)
Guinea pig (4)
Horse (4)
Monkey (1)
Orangutan (3)
Pig (8)
Application
IHC (47)
IHC-Fr (6)
IHC-P (8)
WB (68)
ELISA (14)
ICC (2)
ID (4)
IE (3)
IF (4)
IP (2)
Peptide-ELISA (3)
Host
rabbit (62)
mouse (4)
goat (2)
sheep (9)
Isotype
IgG (60)
IgG2b (4)
Clonality
monoclonal mc (4)
polyclonal pc (73)
Clone
10.32 (4)
Format
AP Conjugated (1)
APC (4)
APC Conjugated (5)
Azide-free (1)
Biotin Conjugated (10)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
FITC Conjugated (12)
HRP Conjugated (8)
PE Conjugated (5)
Unconjugated (28)
Epitope
aa30-150 (10)
aa335-590 (10)
aa32-151 (9)
aa334-589 (9)
aa352-380 (8)
C-Terminus (4)
aa503-552 (4)
Internal (2)
aa24-618 (2)
Val378 (1)
aa329-378 (1)
aa525-536 (1)
aa603-614 (1)
Publications
No (76)
Yes (1)
Showing 1-25 of 77 results

UMOD / Uromodulin Antibody (clone 10.32, FITC) IHC-plus™ LS-B3105
Publications (2)
Publications (2)
Mouse Monoclonal [clone 10.32] (IgG2b) to Human UMOD / Uromodulin
Dog, Human
ELISA IF IHC IHC-Fr IHC-P
FITC Conjugated
50µg 0.1mg/ml  $425.00
Anti-UMOD / Uromodulin antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-UMOD / Uromodulin antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50. This image was taken for the unconjugated form of this product. Other forms have not been tested.

UMOD / Uromodulin Antibody (clone 10.32) IHC-plus™ LS-B2887
Mouse Monoclonal [clone 10.32] (IgG2b) to Human UMOD / Uromodulin
Dog, Human
IF IHC IHC-Fr IHC-P
Unconjugated
50µg 1mg/ml  $425.00
Anti-UMOD / Uromodulin antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
Anti-UMOD / Uromodulin antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.

UMOD / Uromodulin Antibody (clone 10.32) LS-C62644
Mouse Monoclonal [clone 10.32] (IgG2b) to Human UMOD / Uromodulin
Human
IF IHC IHC-Fr IHC-P
Unconjugated
1ml  $375.00

UMOD / Uromodulin Antibody (aa352-380) IHC-plus™ LS-B9021
Rabbit Polyclonal to Human UMOD / Uromodulin
Human
IHC IHC-P WB
Unconjugated
200µl  $425.00
Anti-UMOD / Uromodulin antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
UMOD Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The UMOD antibody detected the UMOD protein (arrow).
Anti-UMOD / Uromodulin antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
UMOD Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The UMOD antibody detected the UMOD protein (arrow).

UMOD / Uromodulin Antibody IHC-plus™ LS-B12306
Rabbit Polyclonal to Human UMOD / Uromodulin
Human
ELISA IHC IHC-P WB
Unconjugated
100µg 100µl  $425.00
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

UMOD / Uromodulin Antibody (aa30-150) LS-C296931
Rabbit Polyclonal (IgG) to Rat UMOD / Uromodulin
Rat
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $315.00; 1ml 0.5mg/ml  $575.00; 10ml 0.5mg/ml  $2,280.00
Western blot of recombinant UMOD / Uromodulin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant UMOD / Uromodulin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

UMOD / Uromodulin Antibody (aa503-552) LS-C107549
Rabbit Polyclonal (IgG) to Human UMOD / Uromodulin
Dog, Guinea pig, Bovine, Horse, Human
WB
Unconjugated
50µg  $365.00
UMOD / Uromodulin antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
UMOD / Uromodulin antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

UMOD / Uromodulin Antibody (clone 10.32, HRP) LS-C62647
Mouse Monoclonal [clone 10.32] (IgG2b) to Human UMOD / Uromodulin
Human
IF IHC IHC-Fr IHC-P
HRP Conjugated
100µg 0.8mg/ml  $345.00

UMOD / Uromodulin Antibody (aa352-380) LS-C326195
Rabbit Polyclonal (IgG) to Human UMOD / Uromodulin
Human
IHC WB
Unconjugated
200µl  $530.00

UMOD / Uromodulin Antibody (aa352-380, Biotin) LS-C273036
Rabbit Polyclonal (IgG) to Human UMOD / Uromodulin
Human
ELISA IHC WB
Biotin Conjugated
200µl  $680.00

UMOD / Uromodulin Antibody (aa352-380, FITC) LS-C273037
Rabbit Polyclonal (IgG) to Human UMOD / Uromodulin
Human
ELISA IHC WB
FITC Conjugated
200µl  $680.00

UMOD / Uromodulin Antibody (aa352-380, Azide-free, HRP) LS-C273038
Rabbit Polyclonal (IgG) to Human UMOD / Uromodulin
Human
IHC WB
HRP Conjugated, Azide-free
200µl 0.5mg/ml  $680.00

UMOD / Uromodulin Antibody (aa352-380, AP) LS-C273034
Rabbit Polyclonal (IgG) to Human UMOD / Uromodulin
Human
ELISA IHC WB
AP Conjugated
200µl  $680.00

UMOD / Uromodulin Antibody (aa352-380, PE) LS-C273039
Rabbit Polyclonal (IgG) to Human UMOD / Uromodulin
Human
ELISA IHC WB
PE Conjugated
200µl  $680.00

UMOD / Uromodulin Antibody (aa352-380, APC) LS-C273035
Rabbit Polyclonal (IgG) to Human UMOD / Uromodulin
Human
ELISA IHC WB
APC Conjugated
200µl  $680.00

UMOD / Uromodulin Antibody (aa24-618) LS-C126349
Sheep Polyclonal (IgG) to Mouse UMOD / Uromodulin
Mouse
ELISA WB
Unconjugated
100µg 500µl 0.2mg/ml  $770.00

UMOD / Uromodulin Antibody IHC-plus™ LS-B12315
Sheep Polyclonal to Human UMOD / Uromodulin
Human
ELISA IHC IHC-P IP WB
Unconjugated
100µg 100µl  $425.00
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

UMOD / Uromodulin Antibody (C-Terminus) LS-C116970
Rabbit Polyclonal to Human UMOD / Uromodulin
Human
WB
Unconjugated
50µg  $365.00
UMOD / Uromodulin antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
UMOD / Uromodulin antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

UMOD / Uromodulin Antibody (Val378) IHC-plus™ LS-B10371
Rabbit Polyclonal to Human UMOD / Uromodulin
Human
IHC IHC-P WB
Unconjugated
50µl  $425.00
Anti-UMOD / Uromodulin antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Western blot of UMOD (V378) pAb in extracts from K562 cells.
Anti-UMOD / Uromodulin antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Western blot of UMOD (V378) pAb in extracts from K562 cells.

UMOD / Uromodulin Antibody LS-C660438
Rabbit Polyclonal (IgG) to Human UMOD / Uromodulin
Human
ELISA IHC IP WB
Unconjugated
100µg  $435.00

UMOD / Uromodulin Antibody LS-C39484
Sheep Polyclonal (IgG) to Human UMOD / Uromodulin
Human
ELISA ID IE IHC
Unconjugated
1000µl  $435.00

UMOD / Uromodulin Antibody (aa335-590) LS-C314997
Rabbit Polyclonal (IgG) to Mouse UMOD / Uromodulin
Mouse
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $545.00; 10ml 0.5mg/ml  $2,160.00
Western blot of recombinant UMOD / Uromodulin.
Western blot of recombinant UMOD / Uromodulin.

UMOD / Uromodulin Antibody LS-C39482
Sheep Polyclonal (IgG) to Human UMOD / Uromodulin
Human
ELISA IHC IHC-Fr
Unconjugated
1000µl  $650.00

UMOD / Uromodulin Antibody LS-C42169
Sheep Polyclonal (IgG) to Human UMOD / Uromodulin
Human
ELISA IHC IHC-Fr
Unconjugated
1000µl  $435.00

UMOD / Uromodulin Antibody LS-C341325
Rabbit Polyclonal to Human UMOD / Uromodulin
Mouse, Rat, Human
IHC WB
Unconjugated
100µl 1mg/ml  $385.00
Showing 1-25 of 77 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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