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UIMC1 / RAP80

ubiquitin interaction motif containing 1

Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. Also weakly binds monoubiquitin but with much less affinity than 'Lys-63'-linked ubiquitin. May interact with monoubiquitinated histones H2A and H2B; the relevance of such results is however unclear in vivo. Does not bind Lys-48'-linked ubiquitin. May indirectly act as a transcriptional repressor by inhibiting the interaction of NR6A1 with the corepressor NCOR1.

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Products

Antibodies (26)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (26)

Recombinant (1)

Target

UIMC1 / RAP80 (29)

Reactivity

Human (26)

Mouse (6)

Rat (3)

Monkey (1)

Application

IHC (8)

IHC-P (7)

WB (20)

Flo (1)

ELISA (4)

ICC (1)

IF (6)

IP (2)

Peptide-ELISA (2)

Host

rabbit (25)

goat (1)

Product Group

IHCPlus (4)

Isotype

IgG (14)

Clonality

polyclonal pc (26)

Format

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

Unconjugated (17)

Epitope

Internal (8)

aa650-C-term (2)

aa535-548 (1)

aa567-601 (1)

aa600-650 (1)

Publications

No (29)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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IHC-plus™ UIMC1 / RAP80 Antibody LS-B2707

(4.0) Rating

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ UIMC1 / RAP80 Antibody (aa535-548) LS-B7372

(4.0) Rating

Antibody:

UIMC1 / RAP80 Goat anti-Human Polyclonal (aa535-548) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µg/$485

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IHC-plus™ UIMC1 / RAP80 Antibody LS-B2706

(4.0) Rating

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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IHC-plus™ UIMC1 / RAP80 Antibody (aa600-650) LS-B15284

(4.0) Rating

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal (aa600-650) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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UIMC1 / RAP80 Antibody LS-C346307

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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UIMC1 / RAP80 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G112735

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

79.5 kDa

Price:

100 µg/$494

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UIMC1 / RAP80 Antibody LS-C672120

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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UIMC1 / RAP80 Antibody (FITC) LS-C672119

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• FITC

• Unconjugated
• FITC

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UIMC1 / RAP80 Antibody (aa650-C-term) LS-C285965

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal (aa650-C-term) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

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UIMC1 / RAP80 Antibody (aa650-C-term) LS-C287625

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal (aa650-C-term) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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UIMC1 / RAP80 Antibody LS-C668296

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

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UIMC1 / RAP80 Antibody LS-C772924

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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UIMC1 / RAP80 Antibody (aa567-601) LS-C344242

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal (aa567-601) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

400 µl/$393

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UIMC1 / RAP80 Antibody LS-C780363

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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UIMC1 / RAP80 Antibody LS-C807097

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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UIMC1 / RAP80 Antibody (Internal) LS-C345853

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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UIMC1 / RAP80 Antibody (Internal, HRP) LS-C480947

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal (Internal) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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UIMC1 / RAP80 Antibody (Internal, Biotin) LS-C480946

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal (Internal) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

UIMC1 / RAP80 Antibody (Internal, FITC) LS-C480945

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal (Internal) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

UIMC1 / RAP80 Antibody (Internal) LS-C345854

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

UIMC1 / RAP80 Antibody (Internal, HRP) LS-C480950

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal (Internal) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

UIMC1 / RAP80 Antibody (Internal, Biotin) LS-C480949

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal (Internal) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

UIMC1 / RAP80 Antibody (Internal, FITC) LS-C480948

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal (Internal) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

UIMC1 / RAP80 Antibody LS-C749512

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

UIMC1 / RAP80 Antibody LS-C661435

Antibody:

UIMC1 / RAP80 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Format:

Unconjugated

Price:

100 µg/$351

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