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UGT1A6

UDP glucuronosyltransferase 1 family, polypeptide A6

UGT1A6 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.

Gene Name: UDP glucuronosyltransferase 1 family, polypeptide A6
Synonyms: UGT1A6, GNT1, HLUGP, UDPGT, UGT1*6, UGT1-06, UGT1A6S, UGT-1F, UGT1.6, UGT1F, UGT1, HLUGP1, UDPGT 1-6
Target Sequences: NM_001072 NP_001063.2 P19224

Publications (1)

1
15-Deoxy-?(12,14)-prostaglandin J(2) induces growth inhibition, cell cycle arrest and apoptosis in human endometrial cancer cell lines. Li H, Narahara H. International journal of molecular medicine. 2013 31:778-88. (WB; Human) [Full Text Article] [PubMed:23403520] Related Antibodies: LS-C109532.

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rabbit (14)
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UGT1A6 Antibody - Sample (30 ug of whole cell lysate). A: A431. B: H1299. 7.5% SDS PAGE. UGT1A6 antibody diluted at 1:1000.
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UGT1A6 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$450
UGT1A6 Antibody - 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UGT1A6 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
UGT1A6 Antibody - 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UGT1A6 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Horse, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Gibbon, Orangutan, Human, Monkey
WB
HRP Conjugated
100 µl/$469
UGT1A6 Antibody - 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UGT1A6 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Horse, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Gibbon, Orangutan, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
UGT1A6 Antibody - 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UGT1A6 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Horse, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Gibbon, Orangutan, Human, Monkey
WB
FITC Conjugated
100 µl/$469
UGT1A6 Antibody - Immunochemical staining of human UGT1A6 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
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UGT1A6 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µl/$412
UGT1A6 Antibody - Immunohistochemistry of paraffin-embedded human uterine cancer using UGT1A6 antibodyat dilution of 1:100 (40x lens).
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UGT1A6 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
UGT1A6 Antibody - Immunohistochemistry image at a dilution of 1:200 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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UGT1A6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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UGT1A6 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
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UGT1A6 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
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UGT1A6 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
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UGT1A6 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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UGT1A6 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
UGT1A6 Antibody
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UGT1A6 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).