UGT1A4

UDP glucuronosyltransferase 1 family, polypeptide A4

UGT1A4 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

UGT1A4 (5)

Publications

No (5)

Tag

6His, N-terminus (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human UGT1A4 Protein (Recombinant GST, N-terminus) (aa34-128) - LS-G62605

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human UGT1A4 Protein (Recombinant 6His, N-terminus) (aa29-534) - LS-G56616

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human UGT1A4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87977

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.03 kDa

Price:

20 µg/$215

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Human UGT1A4 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70779

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57 kDa

Price:

20 µg/$1,107

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UGT1A4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114851

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.03 kDa

Price:

100 µg/$710

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