UGT1A / UGT1A1

UDP glucuronosyltransferase 1 family, polypeptide A1

UGT1A / UGT1A1 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome.

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Products

ELISA Kits (9)

Type

Custom (2)

Sandwich (7)

Target

UGT1A / UGT1A1 (9)

Reactivity

Human (4)

Mouse (1)

Rat (4)

Format

96-Well Microplate (1)

96-Well Strip Plate (8)

Publications

No (8)

Yes (1)

Sample Type

Cell Lysates (2)

Plasma (5)

Serum (5)

Tissue Homogenates (4)

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Rat UGT1A / UGT1A1 (Sandwich ELISA) ELISA Kit - LS-F8467

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$893

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Human UGT1A / UGT1A1 (Sandwich ELISA) ELISA Kit - LS-F8610

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

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Rat UGT1A / UGT1A1 (Sandwich ELISA) ELISA Kit - LS-F16784

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Mouse UGT1A / UGT1A1 (Custom ELISA) ELISA Kit - LS-F16783

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Human UGT1A / UGT1A1 (Sandwich ELISA) ELISA Kit - LS-F35948

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Rat UGT1A / UGT1A1 (Sandwich ELISA) ELISA Kit - LS-F38755

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human UGT1A / UGT1A1 (Custom ELISA) ELISA Kit - LS-F50758

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$923

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Rat UGT1A / UGT1A1 (Sandwich ELISA) ELISA Kit - LS-F54058

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$1,041

Select

Human UGT1A / UGT1A1 (Sandwich ELISA) ELISA Kit - LS-F12906

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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