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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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UGT1A / UGT1A1

UDP glucuronosyltransferase 1 family, polypeptide A1

UGT1A / UGT1A1 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome.

Gene Name: UDP glucuronosyltransferase 1 family, polypeptide A1
Synonyms: UGT1A1, GNT1, HUG-BR1, UDPGT, UDPGT 1-1, UGT1A, BILIQTL1, UGT1, UGT1*1, UGT1-01, UGT-1A, UGT1.1
Target Sequences: NM_000463 NP_000454.1 P22309

Filtered By: None
Target
UGT1A / UGT1A1 (26)
Reactivity
Human (26)
Mouse (4)
Gibbon (3)
Application
IHC (12)
IHC-P (3)
WB (23)
ELISA (9)
ICC (6)
IF (10)
Host
rabbit (25)
goat (1)
Isotype
IgG (21)
Clonality
polyclonal pc (26)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (11)
Epitope
aa65-90 (8)
aa251-300 (4)
aa36-85 (4)
aa60-168 (1)
Publications
No (26)
Showing 1-25 of 26 results

UGT1A / UGT1A1 Antibody (aa65-90) LS-C160417
Rabbit Polyclonal to Human UGT1A / UGT1A1
Human
IF IHC IHC-P WB
Unconjugated
400µl  $305.00
UGT1A1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Confocal immunofluorescence of UGT1A1 Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
UGT1A1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Confocal immunofluorescence of UGT1A1 Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

UGT1A / UGT1A1 Antibody LS-C341955
Rabbit Polyclonal to Human UGT1A / UGT1A1
Human
IHC WB
Unconjugated
100µl 1mg/ml  $385.00

UGT1A / UGT1A1 Antibody LS-C673257
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Human
ELISA IF IHC IHC-P WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image at a dilution of 1:300 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunofluorescence staining of HepG2 cells at a dilution of 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 °C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L) .
Immunohistochemistry image at a dilution of 1:300 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunofluorescence staining of HepG2 cells at a dilution of 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 °C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L) .

UGT1A / UGT1A1 Antibody (HRP) LS-C673258
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Human
HRP Conjugated
50µg  $285.00; 100µg  $385.00

UGT1A / UGT1A1 Antibody (Biotin) LS-C673259
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Human
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

UGT1A / UGT1A1 Antibody LS-C662740
Rabbit Polyclonal to Human UGT1A / UGT1A1
Human
ELISA IHC IHC-P WB
Unconjugated
100µg  $355.00
Immunohistochemistry - Anti-UGT1A1 Picoband antibody
Immunohistochemistry - Anti-UGT1A1 Picoband antibody
Immunohistochemistry - Anti-UGT1A1 Picoband antibody
Immunohistochemistry - Anti-UGT1A1 Picoband antibody

UGT1A / UGT1A1 Antibody (aa65-90) LS-C326170
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Human
ELISA IF IHC WB
Unconjugated
200µl  $530.00

UGT1A / UGT1A1 Antibody (aa65-90, Biotin) LS-C218261
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Human
ELISA ICC IF IHC WB
Biotin Conjugated
200µl  $680.00

UGT1A / UGT1A1 Antibody (aa65-90, FITC) LS-C218262
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Human
ELISA ICC IF IHC WB
FITC Conjugated
200µl  $680.00

UGT1A / UGT1A1 Antibody (aa65-90, AP) LS-C218259
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Human
ELISA ICC IF IHC WB
AP Conjugated
200µl  $680.00

UGT1A / UGT1A1 Antibody (aa65-90, PE) LS-C218266
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Human
ELISA ICC IF IHC WB
PE Conjugated
200µl  $680.00

UGT1A / UGT1A1 Antibody (aa65-90, Azide-free, HRP) LS-C218265
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Human
ELISA ICC IF IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

UGT1A / UGT1A1 Antibody (aa65-90, APC) LS-C218260
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Human
ELISA ICC IF IHC WB
APC Conjugated
200µl  $680.00

UGT1A / UGT1A1 Antibody LS-C334543
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Human
IF IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Western blot analysis of extracts of various cell lines, using UGT1A1 antibody.
Western blot analysis of extracts of various cell lines, using UGT1A1 antibody.

UGT1A / UGT1A1 Antibody (aa36-85) LS-C102087
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Mouse, Human
WB
Unconjugated
50µg  $365.00
UGT1A1 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
UGT1A1 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

UGT1A / UGT1A1 Antibody (aa36-85, HRP) LS-C446357
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Mouse, Human
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
UGT1A1 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
UGT1A1 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

UGT1A / UGT1A1 Antibody (aa36-85, Biotin) LS-C446355
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Mouse, Human
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
UGT1A1 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
UGT1A1 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

UGT1A / UGT1A1 Antibody (aa36-85, FITC) LS-C446356
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Mouse, Human
WB
FITC Conjugated
100µl 1mg/ml  $385.00
UGT1A1 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
UGT1A1 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

UGT1A / UGT1A1 Antibody LS-C482533
Rabbit Polyclonal to Human UGT1A / UGT1A1
Human
WB
Unconjugated
50µl 1mg/ml  $255.00; 100µl 1mg/ml  $295.00; 200µl 1mg/ml  $375.00
Western blot analysis of UGT1A1 expression in HepG2 (A); SHSY5Y (B); mouse liver (C); rat liver (D) whole cell lysates.
Western blot analysis of UGT1A1 expression in HepG2 (A); SHSY5Y (B); mouse liver (C); rat liver (D) whole cell lysates.

UGT1A / UGT1A1 Antibody LS-C668628
Rabbit Polyclonal to Human UGT1A / UGT1A1
Human
WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $275.00
Western blot Image
Western blot Image

UGT1A / UGT1A1 Antibody (aa251-300) LS-C40468
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Human
WB
Unconjugated
100µg  $325.00
UGT1A1 antibody ARP44294_T100-NP_000454-UGT1A1(UDP glucuronosyltransferase 1 family, polypeptide A1) Antibody Western blot of Fetal Liver lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UGT1A1 antibody ARP44294_T100-NP_000454-UGT1A1(UDP glucuronosyltransferase 1 family, polypeptide A1) Antibody Western blot of Fetal Liver lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

UGT1A / UGT1A1 Antibody (aa251-300, HRP) LS-C446360
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Human, Gibbon
WB
HRP Conjugated
100µl 0.65mg/ml  $335.00
UGT1A1 antibody ARP44294_T100-NP_000454-UGT1A1(UDP glucuronosyltransferase 1 family, polypeptide A1) Antibody Western blot of Fetal Liver lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UGT1A1 antibody ARP44294_T100-NP_000454-UGT1A1(UDP glucuronosyltransferase 1 family, polypeptide A1) Antibody Western blot of Fetal Liver lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

UGT1A / UGT1A1 Antibody (aa251-300, Biotin) LS-C446358
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Human, Gibbon
WB
Biotin Conjugated
100µl 1mg/ml  $335.00
UGT1A1 antibody ARP44294_T100-NP_000454-UGT1A1(UDP glucuronosyltransferase 1 family, polypeptide A1) Antibody Western blot of Fetal Liver lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UGT1A1 antibody ARP44294_T100-NP_000454-UGT1A1(UDP glucuronosyltransferase 1 family, polypeptide A1) Antibody Western blot of Fetal Liver lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

UGT1A / UGT1A1 Antibody (aa251-300, FITC) LS-C446359
Rabbit Polyclonal (IgG) to Human UGT1A / UGT1A1
Human, Gibbon
WB
FITC Conjugated
100µl 1mg/ml  $335.00
UGT1A1 antibody ARP44294_T100-NP_000454-UGT1A1(UDP glucuronosyltransferase 1 family, polypeptide A1) Antibody Western blot of Fetal Liver lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UGT1A1 antibody ARP44294_T100-NP_000454-UGT1A1(UDP glucuronosyltransferase 1 family, polypeptide A1) Antibody Western blot of Fetal Liver lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

UGT1A / UGT1A1 Antibody (aa60-168) LS-C184920
Goat Polyclonal (IgG) to Human UGT1A / UGT1A1
Human
WB
Unconjugated
100µg 500µl  $770.00
Showing 1-25 of 26 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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