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UCN3 / SPC

urocortin 3

UCN3 / SPC is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II.

Gene Name: urocortin 3
Synonyms: UCN3, SPC, Stresscopin, Urocortin 3 (stresscopin), Urocortin 3, Urocortin III, Urocortin-3, UCNIII, SCP, Ucn III
Target Sequences: Q969E3 Q969E3

Publications (3)

1
Urocortin 3 Levels Are Impaired in Overweight Humans With and Without Type 2 Diabetes and Modulated by Exercise. Kavalakatt S, Khadir A, Madhu D, Hammad M, Devarajan S, Abubaker J, Al-Mulla F, Tuomilehto J, Tiss A. Frontiers in endocrinology. 2019 November;10: [Full Text Article] [PubMed:31781037] [PMC:PMC6851015]
2
Urocortin 3 overexpression reduces ER stress and heat shock response in 3T3-L1 adipocytes. Sina Kavalakatt, Abdelkrim Khadir, Dhanya Madhu, Heikki A Koistinen , Fahd Al-Mulla, Jaakko Tuomilehto , Jehad Abubaker, Ali Tiss. Scientific reports. 2021 Aug;11:15666. [Full Text Article] [PubMed:34341463] [PMC:PMC8329193]
3
Circulating levels of urocortin neuropeptides are impaired in children with overweight. Sina Kavalakatt, Abdelkrim Khadir, Dhanya Madhu, Sriraman Devarajan, Samia Warsame, Hessa AlKandari, Maria AlMahdi, Heikki A Koistinen, Fahd Al-Mulla, Jaakko Tuomilehto, Jehad Abubaker, Ali Tiss. Obesity (Silver Spring, Md.). 2022 Feburary;30:472-481. [Full Text Article] [PubMed:35088550] [PMC:PMC9305428]

☰ Filters
Antibodies (43)
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UCN3 / SPC (60)
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monoclonal mc (8)
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UCN3 / SPC ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
UCN3 / SPC ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
UCN3 / SPC Antibody - Western blot of recombinant UCN3 / SPC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UCN3 / SPC Rabbit anti-Mouse Polyclonal (aa24-149) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
UCN3 / SPC Antibody - Western blot of recombinant UCN3 / SPC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UCN3 / SPC Rabbit anti-Mouse Polyclonal (aa24-149) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
UCN3 / SPC Antibody - Western blot of recombinant UCN3 / SPC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UCN3 / SPC Rabbit anti-Mouse Polyclonal (aa24-149) (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
UCN3 / SPC Antibody - Western blot of recombinant UCN3 / SPC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UCN3 / SPC Rabbit anti-Mouse Polyclonal (aa24-149) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
UCN3 / SPC Antibody - Western blot of recombinant UCN3 / SPC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UCN3 / SPC Rabbit anti-Mouse Polyclonal (aa24-149) (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781
UCN3 / SPC Antibody - Western blot of recombinant UCN3 / SPC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UCN3 / SPC Rabbit anti-Mouse Polyclonal (aa24-149) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
UCN3 / SPC Antibody - HEK293 lysate (10ug protein in RIPA buffer) over expressing Human UCN3 with DYKDDDDK tag probed with (1ug/ml) in Lane A and probed with anti- DYKDDDDK Tag (1/3000) in lane C. Mock-transfected HEK293 probed (1mg/ml) in Lane B. Primary
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UCN3 / SPC Goat anti-Human Polyclonal (aa106-119) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
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UCN3 / SPC Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
200 µg/$1,027
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UCN3 / SPC Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
200 µg/$1,027
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UCN3 / SPC Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
100 µl/$1,109
UCN3 / SPC Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using UCN3 Polyclonal Antibody at dilution of 1:55(×200)
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UCN3 / SPC Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
UCN3 / SPC Antibody - Western blot of recombinant UCN3 / SPC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UCN3 / SPC Mouse anti-Human Monoclonal (aa22-161) Antibody
Human
WB
Unconjugated
100 µl/$314; 200 µl/$359; 500 µl/$507; 1 ml/$581; 2 ml/$798; 5 ml/$1,296
UCN3 / SPC Antibody - Western blot of recombinant UCN3 / SPC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UCN3 / SPC Mouse anti-Human Monoclonal (aa22-161) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$345; 200 µl/$403; 500 µl/$595; 1 ml/$742; 2 ml/$979; 5 ml/$1,684
UCN3 / SPC Antibody - Western blot of recombinant UCN3 / SPC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UCN3 / SPC Mouse anti-Human Monoclonal (aa22-161) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$325; 200 µl/$373; 500 µl/$536; 1 ml/$628; 2 ml/$860; 5 ml/$1,425
UCN3 / SPC Antibody - Western blot of recombinant UCN3 / SPC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UCN3 / SPC Mouse anti-Human Monoclonal (aa22-161) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$356; 200 µl/$418; 500 µl/$638; 1 ml/$798; 2 ml/$1,035; 5 ml/$1,813
UCN3 / SPC Antibody - Western blot of recombinant UCN3 / SPC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UCN3 / SPC Mouse anti-Human Monoclonal (aa22-161) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$418; 200 µl/$507; 500 µl/$887; 1 ml/$1,051; 2 ml/$1,383; 5 ml/$2,591
UCN3 / SPC Antibody - Western blot of recombinant UCN3 / SPC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UCN3 / SPC Mouse anti-Human Monoclonal (aa22-161) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$418; 200 µl/$507; 500 µl/$887; 1 ml/$1,051; 2 ml/$1,383; 5 ml/$2,591
UCN3 / SPC Antibody - Western blot of recombinant UCN3 / SPC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UCN3 / SPC Mouse anti-Human Monoclonal (aa22-161) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$521; 200 µl/$685; 500 µl/$1,198; 1 ml/$1,481; 2 ml/$2,073; 5 ml/$3,885
UCN3 / SPC Antibody - Western blot of recombinant UCN3 / SPC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UCN3 / SPC Mouse anti-Human Monoclonal (aa22-161) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$418; 200 µl/$507; 500 µl/$887; 1 ml/$1,051; 2 ml/$1,383; 5 ml/$2,591
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UCN3 / SPC Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
200 µg/$1,027
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UCN3 / SPC Rabbit anti-Mouse Polyclonal (Rhodamine) Antibody
Mouse
ELISA
Rhodamine Conjugated
100 µl/$1,109
UCN3 / SPC Antibody - Western Blot; Sample: Recombinant UCN3, Human.
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UCN3 / SPC Rabbit anti-Human Polyclonal (aa22-161) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
UCN3 / SPC Antibody - Western Blot; Sample: Recombinant UCN3, Human.
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UCN3 / SPC Rabbit anti-Human Polyclonal (aa22-161) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
Viewing 1-25 of 60 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).