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UCN3 / SPC
urocortin 3
UCN3 / SPC is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II.
| Gene Name: | urocortin 3 |
| Synonyms: | UCN3, SPC, Stresscopin, Urocortin 3 (stresscopin), Urocortin 3, Urocortin III, Urocortin-3, UCNIII, SCP, Ucn III |
| Target Sequences: | Q969E3 Q969E3 |
Publications (3)
1
Urocortin 3 Levels Are Impaired in Overweight Humans With and Without Type 2 Diabetes and Modulated by Exercise. Kavalakatt S, Khadir A, Madhu D, Hammad M, Devarajan S, Abubaker J, Al-Mulla F, Tuomilehto J, Tiss A. Frontiers in endocrinology. 2019 November;10: [Full Text Article]
[PubMed:31781037]
[PMC:PMC6851015]
2
Urocortin 3 overexpression reduces ER stress and heat shock response in 3T3-L1 adipocytes. Sina Kavalakatt, Abdelkrim Khadir, Dhanya Madhu, Heikki A Koistinen , Fahd Al-Mulla, Jaakko Tuomilehto , Jehad Abubaker, Ali Tiss. Scientific reports. 2021 Aug;11:15666. [Full Text Article]
[PubMed:34341463]
[PMC:PMC8329193]
3
Circulating levels of urocortin neuropeptides are impaired in children with overweight. Sina Kavalakatt, Abdelkrim Khadir, Dhanya Madhu, Sriraman Devarajan, Samia Warsame, Hessa AlKandari, Maria AlMahdi, Heikki A Koistinen, Fahd Al-Mulla, Jaakko Tuomilehto, Jehad Abubaker, Ali Tiss. Obesity (Silver Spring, Md.). 2022 Feburary;30:472-481. [Full Text Article]
[PubMed:35088550]
[PMC:PMC9305428]
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Sandwich
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$610
UCN3 / SPC Rabbit anti-Mouse Polyclonal (aa24-149) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571
UCN3 / SPC Rabbit anti-Mouse Polyclonal (aa24-149) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722
UCN3 / SPC Rabbit anti-Mouse Polyclonal (aa24-149) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611
UCN3 / SPC Rabbit anti-Mouse Polyclonal (aa24-149) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030
UCN3 / SPC Rabbit anti-Mouse Polyclonal (aa24-149) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030
UCN3 / SPC Rabbit anti-Mouse Polyclonal (aa24-149) (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441
UCN3 / SPC Goat anti-Human Polyclonal (aa106-119) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$493
UCN3 / SPC Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
200 µg/$1,109
UCN3 / SPC Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
200 µg/$1,109
UCN3 / SPC Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
100 µl/$1,195
UCN3 / SPC Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
UCN3 / SPC Mouse anti-Human Monoclonal (aa22-161) Antibody
Human
WB
Unconjugated
100 µl/$314; 200 µl/$359; 500 µl/$507; 1 ml/$581
UCN3 / SPC Mouse anti-Human Monoclonal (aa22-161) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$345; 200 µl/$403; 500 µl/$595; 1 ml/$742
UCN3 / SPC Mouse anti-Human Monoclonal (aa22-161) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$325; 200 µl/$373; 500 µl/$536; 1 ml/$628
UCN3 / SPC Mouse anti-Human Monoclonal (aa22-161) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$356; 200 µl/$418; 500 µl/$638; 1 ml/$798
UCN3 / SPC Mouse anti-Human Monoclonal (aa22-161) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$418; 200 µl/$507; 500 µl/$887; 1 ml/$1,051
UCN3 / SPC Mouse anti-Human Monoclonal (aa22-161) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$418; 200 µl/$507; 500 µl/$887; 1 ml/$1,051
UCN3 / SPC Mouse anti-Human Monoclonal (aa22-161) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$521; 200 µl/$685; 500 µl/$1,198; 1 ml/$1,481
UCN3 / SPC Mouse anti-Human Monoclonal (aa22-161) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$418; 200 µl/$507; 500 µl/$887; 1 ml/$1,051
UCN3 / SPC Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
200 µg/$1,109
UCN3 / SPC Rabbit anti-Mouse Polyclonal (Rhodamine) Antibody
Mouse
ELISA
Rhodamine Conjugated
100 µl/$1,195
UCN3 / SPC Rabbit anti-Human Polyclonal (aa22-161) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561
UCN3 / SPC Rabbit anti-Human Polyclonal (aa22-161) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596
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