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UCN2 / SRP

urocortin 2

UCN2 / SRP is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II.

Gene Name: urocortin 2
Synonyms: UCN2, SRP, Ucn II, UCN-II, UCNI, Urocortin 2, UR, Urocortin-related peptide, Stresscopin-related peptide, Urocortin II, Urocortin-2, URP
Target Sequences: NM_033199 NP_149976.1 Q96RP3

Publications (1)

1
Circulating levels of urocortin neuropeptides are impaired in children with overweight. Sina Kavalakatt, Abdelkrim Khadir, Dhanya Madhu, Sriraman Devarajan, Samia Warsame, Hessa AlKandari, Maria AlMahdi, Heikki A Koistinen, Fahd Al-Mulla, Jaakko Tuomilehto, Jehad Abubaker, Ali Tiss. Obesity (Silver Spring, Md.). 2022 Feburary;30:472-481. [Full Text Article] [PubMed:35088550] [PMC:PMC9305428]

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
UCN2 / SRP (6)
No (6)
GST (1)
His (3)
Myc-DDK (Flag) (2)
Human (3)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
UCN2 / SRP Protein - 12.5% SDS-PAGE of human UCN2 stained with Coomassie Blue
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Wheat Germ Extract
GST
38.5 kDa
2 µg/$439
UCN2 / SRP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
10 kDa
20 µg/$150
UCN2 / SRP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
10 kDa
100 µg/$494
UCN2 / SRP Protein
Select
E. coli
His
10.2 kDa
10 µg/$277; 50 µg/$420; 100 µg/$670; 200 µg/$837; 1 mg/$1,928; 500 µg/$1,474; 5 mg/$2,927; 2 mg/$2,113
UCN2 / SRP Protein - Recombinant Urocortin 2 By SDS-PAGE
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E. coli
His
11.3 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
UCN2 / SRP Protein - Recombinant Urocortin 2 By SDS-PAGE
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E. coli
His
10.6 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).