UCHL3

ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)

Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. Has a 10-fold preference for Arg and Lys at position P3", and exhibits a preference towards 'Lys-48'-linked Ubiquitin chains. Deubiquitinates ENAC in apical compartments, thereby regulating apical membrane recycling. Indirectly increases the phosphorylation of IGFIR, AKT and FOXO1 and promotes insulin-signaling and insulin-induced adipogenesis. Required for stress-response retinal, skeletal muscle and germ cell maintenance. May be involved in working memory. Can hydrolyze UBB(+1), a mutated form of ubiquitin which is not effectively degraded by the proteasome and is associated with neurogenerative disorders.

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Products

Antibodies (55)

Proteins (13)

ELISA Kits (1)

Type

Custom (1)

Over-Expression Lysate (2)

Primary (55)

Recombinant (11)

Target

UCHL3 (69)

Reactivity

Human (39)

Mouse (25)

Rat (27)

Bovine (8)

Chicken (1)

Chimpanzee (6)

Dog (9)

Gibbon (3)

Guinea pig (6)

Hamster (1)

Horse (8)

Monkey (8)

Orangutan (3)

Pig (7)

Rabbit (7)

Zebrafish (7)

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Application

IHC (21)

IHC-Fr (1)

IHC-P (18)

WB (44)

ELISA (14)

IF (1)

IP (7)

Peptide-ELISA (1)

Host

rabbit (52)

mouse (3)

Product Group

IHCPlus (6)

Isotype

IgG (14)

IgG2a,k (1)

IgG2b,k (1)

Clonality

monoclonal mc (3)

polyclonal pc (52)

Clone

4E9 (1)

Format

96-Well Microplate (1)

APC (2)

APC Conjugated (2)

Biotin Conjugated (5)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (2)

Unconjugated (32)

Epitope

aa2-230 (17)

C-Terminus (5)

N-Terminus (4)

aa101-150 (4)

Internal (2)

Leu220 (1)

aa1-220 (1)

aa1-50 (1)

aa174-224 (1)

Publications

No (68)

Yes (1)

Tag

6His, C-terminus (2)

GST (1)

GST, N-terminus (1)

His (5)

His,N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (9)

Mouse (1)

Rat (2)

Source

293T Cells (1)

E. coli (8)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (2)

Biologically Active

Biologically active (1)

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IHC-plus™ UCHL3 Antibody (C-Terminus) LS-A8724

Fast Shipping

(5.0) Rating

(4) Publication(s)

Antibody:

UCHL3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey

Applications:

IF, IHC, IHC-Fr, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ UCHL3 Antibody (Internal) LS-A8555

Fast Shipping

(4.0) Rating

Antibody:

UCHL3 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Dog, Bovine, Horse, Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ UCHL3 Antibody (Internal) LS-A8557

Fast Shipping

(4.0) Rating

Antibody:

UCHL3 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Chicken, Mouse, Dog, Rat, Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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UCHL3 Antibody (C-Terminus) LS-B12741

Antibody:

UCHL3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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UCHL3 Antibody (C-Terminus, HRP) LS-C466104

Antibody:

UCHL3 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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UCHL3 Antibody (C-Terminus, Biotin) LS-C466102

Antibody:

UCHL3 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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UCHL3 Antibody (C-Terminus, FITC) LS-C466103

Antibody:

UCHL3 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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IHC-plus™ UCHL3 Antibody LS-B7856

(4.0) Rating

Antibody:

UCHL3 Mouse anti-Human Monoclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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UCHL3 Antibody (N-Terminus) LS-B4688

Antibody:

UCHL3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Zebrafish, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

Select

UCHL3 Antibody (N-Terminus, HRP) LS-C465349

Antibody:

UCHL3 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Monkey, Orangutan, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

UCHL3 Antibody (N-Terminus, Biotin) LS-C465347

Antibody:

UCHL3 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Monkey, Orangutan, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

UCHL3 Antibody (N-Terminus, FITC) LS-C465348

Antibody:

UCHL3 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Monkey, Orangutan, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

UCHL3 Antibody LS-C489729

Antibody:

UCHL3 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µl/$412

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Human UCHL3 Protein (Recombinant His,N-terminus) (aa2-230) - LS-G15806

Source:

E. coli

Tag:

His,N-terminus

Molecular Weight:

27.6 kDa

Price:

10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723

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UCHL3 Antibody LS-C489726

Antibody:

UCHL3 Rabbit anti-Rat Polyclonal Antibody

Reactivity:

Rat

Applications:

ELISA, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µl/$412

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UCHL3 Antibody LS-C661415

Antibody:

UCHL3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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UCHL3 Antibody LS-C409692

Antibody:

UCHL3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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UCHL3 Antibody (clone 4E9) LS-C198401

Antibody:

UCHL3 Mouse anti-Human Monoclonal (4E9) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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UCHL3 Antibody (aa174-224) LS-C289657

Antibody:

UCHL3 Rabbit anti-Human Polyclonal (aa174-224) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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UCHL3 Antibody (aa1-220) LS-C376982

Antibody:

UCHL3 Rabbit anti-Human Polyclonal (aa1-220) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

UCHL3 Antibody LS-C482972

Antibody:

UCHL3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

Select

UCHL3 Antibody LS-C489724

Antibody:

UCHL3 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

Select

UCHL3 Antibody LS-C489730

Antibody:

UCHL3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µl/$412

Select

UCHL3 Antibody LS-C772437

Antibody:

UCHL3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

UCHL3 Antibody (Leu220) LS-C76684

Antibody:

UCHL3 Rabbit anti-Human Polyclonal (Leu220) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$688

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