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UBR4

ubiquitin protein ligase E3 component n-recognin 4

E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling. May play a role in activation of FAK in response to cell-matrix interactions. Mediates ubiquitination of ACLY, leading to its subsequent degradation.

Gene Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: UBR4, p600, RBAF600, N-recognin-4, Zinc finger, UBR1 type 1, ZUBR1, RP5-1126H10.1, KIAA0462, KIAA1307
Target Sequences: AF055010 AAC09360.1 Q5T4S7

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Proteins (2)
Recombinant (2)
UBR4 (2)
No (2)
GST, N-terminus (1)
His-S (1)
Human (2)
E. coli (1)
Wheat Germ Extract (1)
UBR4 Protein - Recombinant  Ubiquitin Protein Ligase E3 Component N-Recognin 4 By SDS-PAGE
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E. coli
His-S
33.5 kDa
10 µg/$271; 50 µg/$422; 100 µg/$674; 200 µg/$841; 1 mg/$1,880
UBR4 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue
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Wheat Germ Extract
GST, N-terminus
10 µg/$461; 25 µg/$611
Viewing 1-2 of 2 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).