UBR4

ubiquitin protein ligase E3 component n-recognin 4

E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling. May play a role in activation of FAK in response to cell-matrix interactions. Mediates ubiquitination of ACLY, leading to its subsequent degradation.

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Proteins (2)

Type

Recombinant (2)

Target

UBR4 (2)

Publications

No (2)

Tag

GST, N-terminus (1)

His-S (1)

Species

Human (2)

Source

E. coli (1)

Wheat Germ Extract (1)

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Human UBR4 Protein (Recombinant GST, N-terminus) (aa94-190) - LS-G61968

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human UBR4 Protein (Recombinant His-S) (aa124-396) - LS-G26088

Source:

E. coli

Tag:

His-S

Molecular Weight:

33.5 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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