UBR2

ubiquitin protein ligase E3 component n-recognin 2

E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.

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Products

Proteins (2)

Type

Recombinant (2)

Target

UBR2 (2)

Publications

No (2)

Tag

GST (1)

GST, N-terminus (1)

Species

Human (2)

Source

Wheat Germ Extract (2)

Purification

Purified (1)

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Human UBR2 Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G61959

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human UBR2 Protein (Recombinant GST) (Full Length) - LS-G32792

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

76.4 kDa

Price:

10 µg/$479; 25 µg/$670

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