UBE2S / E2 EPF

ubiquitin-conjugating enzyme E2S

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes 'Lys-11'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating 'Lys-11'-linked polyubiquitin chains initiated by the E2 enzyme UBE2C/UBCH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit. Also acts by elongating ubiquitin chains initiated by the E2 enzyme UBE2D1/UBCH5 in vitro; it is however unclear whether UBE2D1/UBCH5 acts as a E2 enzyme for the APC/C in vivo. Also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, except 'Lys-48'-linked polyubiquitination.

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Products

Antibodies (57)

Proteins (10)

Type

Over-Expression Lysate (2)

Primary (57)

Recombinant (8)

Target

UBE2S / E2 EPF (67)

Reactivity

Human (57)

Mouse (11)

Rat (8)

Bovine (4)

Chimpanzee (3)

Dog (1)

Gibbon (3)

Guinea pig (3)

Horse (3)

Monkey (5)

Pig (3)

Rabbit (3)

Xenopus (3)

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Application

IHC (19)

IHC-P (5)

WB (53)

Flo (9)

ELISA (25)

ICC (10)

IF (9)

IP (11)

Peptide-ELISA (1)

Host

rabbit (43)

mouse (13)

goat (1)

Product Group

IHCPlus (1)

Isotype

IgG (30)

IgG1 (10)

IgG1,k (1)

IgG2a,k (1)

Clonality

monoclonal mc (13)

polyclonal pc (44)

Clone

2G7 (1)

OTI1B5 (2)

OTI4B8 (2)

OTI4E4 (2)

OTI4G2 (2)

OTI4H3 (2)

Format

APC (1)

APC Conjugated (4)

Azide-free (3)

Biotin Conjugated (5)

Carrier-free (5)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (4)

Unconjugated (32)

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Epitope

aa10-40 (7)

aa183-210 (7)

aa192-222 (7)

N-Terminus (4)

aa1-222 (1)

aa1-50 (1)

aa172-222 (1)

aa2-14 (1)

Publications

No (67)

Tag

GST (1)

GST, N-terminus (3)

His (1)

His-T7, N-terminus (2)

Myc-DDK (Flag) (3)

Species

Human (8)

Mouse (1)

Source

293T Cells (1)

E. coli (6)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (2)

Select

UBE2S / E2 EPF Antibody (aa10-40) LS-C99505

Antibody:

UBE2S / E2 EPF Rabbit anti-Human Polyclonal (aa10-40) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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UBE2S / E2 EPF Antibody (aa2-14) LS-C54752

Antibody:

UBE2S / E2 EPF Goat anti-Human Polyclonal (aa2-14) Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Human

Applications:

IF, Peptide-ELISA

Format:

Unconjugated

Price:

100 µg/$503

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UBE2S / E2 EPF Antibody LS-C113040

Antibody:

UBE2S / E2 EPF Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

Unconjugated

Price:

50 µl/$303; 100 µl/$365

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UBE2S / E2 EPF Antibody (aa1-222) LS-C132795

Antibody:

UBE2S / E2 EPF Mouse anti-Human Monoclonal (aa1-222) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, WB

Format:

Unconjugated

Price:

50 µl/$525

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IHC-plus™ UBE2S / E2 EPF Antibody (aa183-210) LS-B13775

(4.0) Rating

Antibody:

UBE2S / E2 EPF Rabbit anti-Human Polyclonal (aa183-210) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$525

Select

UBE2S / E2 EPF Antibody (clone OTI4G2) LS-C174207

Antibody:

UBE2S / E2 EPF Mouse anti-Human Monoclonal (OTI4G2) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated

Price:

100 µl/$434

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UBE2S / E2 EPF Antibody (clone OTI4G2, Carrier-free) LS-C797609

Antibody:

UBE2S / E2 EPF Mouse anti-Human Monoclonal (Carrier-free) (OTI4G2) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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UBE2S / E2 EPF Antibody (clone OTI4H3) LS-C337835

Antibody:

UBE2S / E2 EPF Mouse anti-Human Monoclonal (OTI4H3) Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

Flo, IF, WB

Format:

Unconjugated

Price:

100 µl/$434

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UBE2S / E2 EPF Antibody (clone OTI4H3, Carrier-free) LS-C787473

Antibody:

UBE2S / E2 EPF Mouse anti-Human Monoclonal (Carrier-free) (OTI4H3) Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

Flo, IF, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

UBE2S / E2 EPF Antibody (clone OTI4B8) LS-C174196

Antibody:

UBE2S / E2 EPF Mouse anti-Human Monoclonal (OTI4B8) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

UBE2S / E2 EPF Antibody (clone OTI4B8, Carrier-free) LS-C787460

Antibody:

UBE2S / E2 EPF Mouse anti-Human Monoclonal (Carrier-free) (OTI4B8) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

UBE2S / E2 EPF Antibody (clone OTI1B5) LS-C174195

Antibody:

UBE2S / E2 EPF Mouse anti-Human Monoclonal (OTI1B5) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

UBE2S / E2 EPF Antibody (clone OTI1B5, Carrier-free) LS-C787459

Antibody:

UBE2S / E2 EPF Mouse anti-Human Monoclonal (Carrier-free) (OTI1B5) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

UBE2S / E2 EPF Antibody (aa192-222) LS-C99506

Antibody:

UBE2S / E2 EPF Rabbit anti-Human Polyclonal (aa192-222) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

UBE2S / E2 EPF Antibody (aa10-40) LS-C329010

Antibody:

UBE2S / E2 EPF Rabbit anti-Human Polyclonal (aa10-40) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

UBE2S / E2 EPF Antibody (aa10-40, Biotin) LS-C284003

Antibody:

UBE2S / E2 EPF Rabbit anti-Human Polyclonal (aa10-40) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

UBE2S / E2 EPF Antibody (aa10-40, FITC) LS-C284005

Antibody:

UBE2S / E2 EPF Rabbit anti-Human Polyclonal (aa10-40) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

UBE2S / E2 EPF Antibody (aa10-40, APC) LS-C284004

Antibody:

UBE2S / E2 EPF Rabbit anti-Human Polyclonal (aa10-40) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

UBE2S / E2 EPF Antibody (aa10-40, PE) LS-C284007

Antibody:

UBE2S / E2 EPF Rabbit anti-Human Polyclonal (aa10-40) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

UBE2S / E2 EPF Antibody (aa10-40, Azide-free, HRP) LS-C284006

Antibody:

UBE2S / E2 EPF Rabbit anti-Human Polyclonal (aa10-40) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

UBE2S / E2 EPF Antibody (aa192-222) LS-C329011

Antibody:

UBE2S / E2 EPF Rabbit anti-Human Polyclonal (aa192-222) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

UBE2S / E2 EPF Antibody (aa192-222, APC) LS-C284009

Antibody:

UBE2S / E2 EPF Rabbit anti-Human Polyclonal (aa192-222) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• APC

• Unconjugated
• APC

Select

UBE2S / E2 EPF Antibody LS-C661386

Antibody:

UBE2S / E2 EPF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

UBE2S / E2 EPF Antibody LS-C676674

Antibody:

UBE2S / E2 EPF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

UBE2S / E2 EPF Antibody (clone OTI4E4) LS-C174206

Antibody:

UBE2S / E2 EPF Mouse anti-Human Monoclonal (OTI4E4) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µl/$434

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