UBE2L3 / UBCH7

ubiquitin-conjugating enzyme E2L 3

Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PARK2 and ARIH1, that function like function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

UBE2L3 / UBCH7 (6)

Publications

No (6)

Tag

GST (1)

His-S (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human UBE2L3 / UBCH7 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67272

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.7 kDa

Price:

20 µg/$1,107

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Human UBE2L3 / UBCH7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79454

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.7 kDa

Price:

20 µg/$150

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Human UBE2L3 / UBCH7 Protein (Recombinant GST) (Full Length) - LS-G30826

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

42.68 kDa

Price:

10 µg/$479; 25 µg/$670

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Human UBE2L3 / UBCH7 Protein (Recombinant His-S) (aa4-154) - LS-G25485

Source:

E. coli

Tag:

His-S

Molecular Weight:

25.0 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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UBE2L3 / UBCH7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100027

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.7 kDa

Price:

100 µg/$494

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Human UBE2L3 / UBCH7 Protein (Recombinant) - LS-G3588

Source:

E. coli

Tag:

None

Price:

100 µg/$317; 500 µg/$526; 20 µg/$245

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