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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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UBE2L3 / UBCH7

ubiquitin-conjugating enzyme E2L 3

Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PARK2 and ARIH1, that function like function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis.

Gene Name: ubiquitin-conjugating enzyme E2L 3
Synonyms: UBE2L3, E2-F1, L-UBC, UBCH7, UBCE7, Ubiquitin carrier protein L3, UbcM4, Ubiquitin-protein ligase L3
Target Sequences: NM_003347 NP_003338.1 P68036

Filtered by: None
Type
Over-Expression Lysate (3)
Recombinant (7)
Target
UBE2L3 / UBCH7 (10)
Tag
GST (1)
His (1)
His + S (1)
Myc + DDK (4)
Species
Human (8)
Source
293T Cells (1)
E. coli (4)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purification
Purified (5)
Biologically Active
Biologically active (1)
Showing 1-10 of 10 results

UBE2L3 / UBCH7 Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G103752
HEK 293 Cells
Myc + DDK
13.7 kDa
100µg  $345.00

Human UBE2L3 / UBCH7 Protein (Recombinant) - LS-G4825
None
Biologically active
17.861 kDa
3nmol  $455.00

Human UBE2L3 / UBCH7 Protein (Recombinant) - LS-G3588
E. coli
None
100µg 1mg/ml  $275.00; 0.5mg 1mg/ml  $485.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Human UBE2L3 / UBCH7 Protein (Recombinant GST) (Full Length) - LS-G30826
Wheat Germ Extract
GST
42.68 kDa
10µg  $415.00; 25µg  $590.00
12.5% SDS-PAGE of human UBE2L3 stained with Coomassie Blue

Human UBE2L3 / UBCH7 Protein (Recombinant) - LS-G17562
E. coli
None
10µg  $195.00; 50µg  $255.00; 1mg  $1,890.00

Human UBE2L3 / UBCH7 Protein (Recombinant His) - LS-G17564
E. coli
His
10µg  $195.00; 50µg  $255.00; 1mg  $2,040.00

Human UBE2L3 / UBCH7 Protein (Recombinant His + S) (aa4-154) - LS-G25485
E. coli
His + S
25.0 kDa
10µg  $285.00; 50µg  $465.00; 100µg  $620.00; 200µg  $905.00; 1mg  $2,310.00
Recombinant Ubiquitin Conjugating Enzyme E2L3 By SDS-PAGE

Human UBE2L3 / UBCH7 Protein (Recombinant Myc + DDK) (Full Length) - LS-G67272
HEK 293 Cells
Myc + DDK
17.7 kDa
20µg  $815.00
Purified recombinant protein UBE2L3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining

Human UBE2L3 / UBCH7 Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G79454
293T Cells
Myc + DDK
17.7 kDa
20µg  $195.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

UBE2L3 / UBCH7 Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G100027
HEK 293 Cells
Myc + DDK
17.7 kDa
100µg  $345.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Showing 1-10 of 10 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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