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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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UBE2K / LIG

ubiquitin-conjugating enzyme E2K

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains. Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. Ubiquitinates huntingtin. May mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. Proposed to be involved in ubiquitination and proteolytic processing of NF-kappa-B; in vitro supports ubiquitination of NFKB1. In case of infection by cytomegaloviruses may be involved in the US11-dependent degradation of MHC class I heavy chains following their export from the ER to the cytosol. In case of viral infections may be involved in the HPV E7 protein-dependent degradation of RB1.

Gene Name: ubiquitin-conjugating enzyme E2K
Synonyms: UBE2K, E2-25K, E2(25K), HIP2, HYPG, LIG, UBC1, Ubiquitin-protein ligase, HIP-2, Ubiquitin carrier protein
Target Sequences: NM_005339 NP_005330.1 P61086

Filtered By: None
Target
UBE2K / LIG (43)
Reactivity
Human (43)
Mouse (22)
Rat (22)
Bat (13)
Bovine (17)
Chicken (14)
Chimpanzee (12)
Dog (17)
Drosophila (4)
Gibbon (6)
Goat (17)
Guinea pig (16)
Hamster (17)
Horse (17)
Monkey (18)
Pig (17)
Rabbit (17)
Xenopus (14)
Zebrafish (18)
Application
IHC (11)
IHC-P (9)
WB (40)
DB (2)
ELISA (18)
IP (1)
Peptide-ELISA (1)
Host
rabbit (38)
mouse (4)
goat (1)
Isotype
IgG (30)
IgG1 (3)
IgG2a,k (1)
Clonality
monoclonal mc (4)
polyclonal pc (39)
Clone
1D10 (1)
757C3a (3)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (7)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (1)
Unconjugated (19)
Epitope
aa2-30 (8)
C-Terminus (4)
N-Terminus (4)
aa108-157 (4)
aa36-85 (4)
Arg11 (1)
aa144-157 (1)
aa150-200 (1)
Publications
No (43)
Showing 1-25 of 43 results

UBE2K / LIG Antibody (aa144-157) IHC-plus™ LS-B4927
Goat Polyclonal to Human UBE2K / LIG
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Hamster, Bat, Bovine, Rabbit, Mouse, Goat, Dog, Human, Monkey
IHC IHC-P Peptide-ELISA WB
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-UBE2K / HIP2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Anti-UBE2K / HIP2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Anti-UBE2K / HIP2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Anti-UBE2K / HIP2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.

UBE2K / LIG Antibody (clone 757C3a) LS-C76656
Mouse Monoclonal [clone 757C3a] (IgG1) to Human UBE2K / LIG
Human
WB
Unconjugated
50µg 0.1mg/ml  $385.00

UBE2K / LIG Antibody (C-Terminus) IHC-plus™ LS-B10316
Rabbit Polyclonal to Human UBE2K / LIG
Zebrafish, Pig, Horse, Bat, Rat, Hamster, Rabbit, Mouse, Goat, Dog, Guinea pig, Bovine, Human, Monkey
IHC IHC-P WB
Unconjugated
50µg  $485.00
Anti-UBE2K / LIG antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UBE2K / HIP2 antibody Western blot of Transfected 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-UBE2K / LIG antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UBE2K / HIP2 antibody Western blot of Transfected 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

UBE2K / LIG Antibody (C-Terminus, HRP) LS-C444602
Rabbit Polyclonal to Human UBE2K / LIG
Zebrafish, Rat, Hamster, Pig, Horse, Bat, Rabbit, Mouse, Goat, Dog, Guinea pig, Bovine, Human, Monkey, Chimpanzee
IHC IHC-P WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
Anti-UBE2K / LIG antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UBE2K / HIP2 antibody Western blot of Transfected 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-UBE2K / LIG antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UBE2K / HIP2 antibody Western blot of Transfected 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

UBE2K / LIG Antibody (C-Terminus, Biotin) LS-C444601
Rabbit Polyclonal to Human UBE2K / LIG
Zebrafish, Rat, Hamster, Pig, Horse, Bat, Rabbit, Mouse, Goat, Dog, Guinea pig, Bovine, Human, Monkey, Chimpanzee
IHC IHC-P WB
Biotin Conjugated
100µl 1mg/ml  $385.00
Anti-UBE2K / LIG antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UBE2K / HIP2 antibody Western blot of Transfected 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-UBE2K / LIG antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UBE2K / HIP2 antibody Western blot of Transfected 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

UBE2K / LIG Antibody (C-Terminus, FITC) LS-C444603
Rabbit Polyclonal to Human UBE2K / LIG
Zebrafish, Rat, Hamster, Pig, Horse, Bat, Rabbit, Mouse, Goat, Dog, Guinea pig, Bovine, Human, Monkey, Chimpanzee
IHC IHC-P WB
FITC Conjugated
100µl 1mg/ml  $385.00
Anti-UBE2K / LIG antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UBE2K / HIP2 antibody Western blot of Transfected 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-UBE2K / LIG antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UBE2K / HIP2 antibody Western blot of Transfected 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

UBE2K / LIG Antibody (aa108-157) IHC-plus™ LS-B10332
Rabbit Polyclonal (IgG) to Human UBE2K / LIG
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Hamster, Bat, Bovine, Rabbit, Mouse, Goat, Dog, Guinea pig, Human, Monkey
IHC IHC-P WB
Unconjugated
50µg  $485.00
Anti-UBE2K / LIG antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UBE2K / HIP2 antibody Western blot of Fetal liver lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-UBE2K / LIG antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UBE2K / HIP2 antibody Western blot of Fetal liver lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

UBE2K / LIG Antibody (aa108-157, HRP) LS-C464436
Rabbit Polyclonal (IgG) to Human UBE2K / LIG
Xenopus, Chicken, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Goat, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
IHC IHC-P WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
Anti-UBE2K / LIG antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UBE2K / HIP2 antibody Western blot of Fetal liver lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-UBE2K / LIG antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UBE2K / HIP2 antibody Western blot of Fetal liver lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

UBE2K / LIG Antibody (aa108-157, Biotin) LS-C464434
Rabbit Polyclonal (IgG) to Human UBE2K / LIG
Xenopus, Chicken, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Goat, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
IHC IHC-P WB
Biotin Conjugated
100µl 1mg/ml  $385.00
Anti-UBE2K / LIG antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UBE2K / HIP2 antibody Western blot of Fetal liver lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-UBE2K / LIG antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UBE2K / HIP2 antibody Western blot of Fetal liver lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

UBE2K / LIG Antibody (aa108-157, FITC) LS-C464435
Rabbit Polyclonal (IgG) to Human UBE2K / LIG
Xenopus, Chicken, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Goat, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
IHC IHC-P WB
FITC Conjugated
100µl 1mg/ml  $385.00
Anti-UBE2K / LIG antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UBE2K / HIP2 antibody Western blot of Fetal liver lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-UBE2K / LIG antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
UBE2K / HIP2 antibody Western blot of Fetal liver lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

UBE2K / LIG Antibody LS-C661383
Rabbit Polyclonal (IgG) to Human UBE2K / LIG
Human
ELISA IHC WB
Unconjugated
100µg  $435.00

UBE2K / LIG Antibody LS-C192361
Rabbit Polyclonal to Human UBE2K / LIG
Mouse, Rat, Human
IHC WB
Unconjugated
100µl  $385.00
Western blot of UBE2K pAb in extracts from human brain tissue.
Western blot of UBE2K pAb in extracts from human brain tissue.

UBE2K / LIG Antibody (clone 1D10) LS-C197411
Mouse Monoclonal [clone 1D10] (IgG2a,k) to Human UBE2K / LIG
Human
ELISA WB
Unconjugated
100µg  $355.00
Detection limit for recombinant GST tagged UBE2K is 0.1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged UBE2K is 0.1 ng/ml as a capture antibody.

UBE2K / LIG Antibody LS-C285693
Rabbit Polyclonal (IgG) to Human UBE2K / LIG
Human
ELISA WB
Unconjugated
50µg  $285.00; 100µg  $385.00

UBE2K / LIG Antibody (FITC) LS-C317231
Rabbit Polyclonal (IgG) to Human UBE2K / LIG
Human
ELISA WB
FITC Conjugated
50µg  $285.00; 100µg  $385.00

UBE2K / LIG Antibody (aa2-30) LS-C326134
Rabbit Polyclonal (IgG) to Human UBE2K / LIG
Human
ELISA WB
Unconjugated
200µl  $530.00

UBE2K / LIG Antibody (aa2-30, Biotin) LS-C272899
Rabbit Polyclonal (IgG) to Human UBE2K / LIG
Human
ELISA WB
Biotin Conjugated
200µl  $680.00

UBE2K / LIG Antibody (aa2-30, FITC) LS-C272900
Rabbit Polyclonal (IgG) to Human UBE2K / LIG
Human
ELISA WB
FITC Conjugated
200µl  $680.00

UBE2K / LIG Antibody (aa2-30, PE) LS-C272902
Rabbit Polyclonal (IgG) to Human UBE2K / LIG
Human
ELISA WB
PE Conjugated
200µl  $680.00

UBE2K / LIG Antibody (aa2-30, Azide-free, HRP) LS-C272901
Rabbit Polyclonal (IgG) to Human UBE2K / LIG
Human
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00

UBE2K / LIG Antibody (aa2-30, AP) LS-C272897
Rabbit Polyclonal (IgG) to Human UBE2K / LIG
Human
ELISA WB
AP Conjugated
200µl  $680.00

UBE2K / LIG Antibody (aa2-30, APC) LS-C272898
Rabbit Polyclonal (IgG) to Human UBE2K / LIG
Human
ELISA WB
APC Conjugated
200µl  $680.00

UBE2K / LIG Antibody (Arg11) LS-C40067
Rabbit Polyclonal to Human UBE2K / LIG
Mouse, Rat, Human, Monkey
ELISA WB
Unconjugated
100µl  $530.00

UBE2K / LIG Antibody (clone 757C3a) LS-C342453
Mouse Monoclonal [clone 757C3a] (IgG1) to Human UBE2K / LIG
Human
DB WB
Unconjugated
100µg 0.1mg/ml  $375.00
Western blot analysis of immunized recombinant protein, using anti-HIP2 monoclonal antibody.
Western blot analysis of immunized recombinant protein, using anti-HIP2 monoclonal antibody.

UBE2K / LIG Antibody (aa150-200) LS-C290771
Rabbit Polyclonal to Human UBE2K / LIG
Xenopus, Chicken, Zebrafish, Mouse, Rat, Human
IP WB
Unconjugated
100µl 1mg/ml  $395.00
Detection of Human and Mouse E2-25K by Western Blot. Samples: Whole cell lysate (50 ug) from 293T, HeLa, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-E2-25K antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
Detection of Human E2-25K by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from 293T cells. Antibodies: Affinity purified rabbit anti-E2-25K antibody used for IP at 6 ug/mg lysate. E2-25K was inefficiently immunoprecipitated by rabbit anti-E2-25K antibody BL14896. For blotting immunoprecipitated E2-25K, was used at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Detection of Human and Mouse E2-25K by Western Blot. Samples: Whole cell lysate (50 ug) from 293T, HeLa, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-E2-25K antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
Detection of Human E2-25K by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from 293T cells. Antibodies: Affinity purified rabbit anti-E2-25K antibody used for IP at 6 ug/mg lysate. E2-25K was inefficiently immunoprecipitated by rabbit anti-E2-25K antibody BL14896. For blotting immunoprecipitated E2-25K, was used at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Showing 1-25 of 43 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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