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UBE2E3
ubiquitin-conjugating enzyme E2E 3
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
| Gene Name: | ubiquitin-conjugating enzyme E2E 3 |
| Synonyms: | UBE2E3, Ubiquitin carrier protein E3, UbcM2, Ubiquitin-protein ligase E3, UBCH9, UBCE4 |
| Target Sequences: | NM_006357 NP_006348.1 Q969T4 |
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