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UBE1L2 / UBE1L2

ubiquitin-like modifier activating enzyme 6

Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Essential for embryonic development. Required for UBD/FAT10 conjugation. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility.

Gene Name: ubiquitin-like modifier activating enzyme 6
Synonyms: UBA6, FLJ10808, Monocyte protein 4, MOP-4, Ubiquitin-activating enzyme 6, E1-L2, MOP4, UBE1L2
Target Sequences: NM_018227 NP_060697.4 A0AVT1

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
UBE1L2 / UBE1L2 (6)
No (6)
GST (2)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (3)
Purified (2)
UBE1L2 / UBE1L2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
UBE1L2 / UBE1L2 Protein - Purified recombinant protein UBA6 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
117.8 kDa
20 µg/$1,107
UBE1L2 / UBE1L2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
117.8 kDa
20 µg/$150
UBE1L2 / UBE1L2 Protein - 12.5% SDS-PAGE of human FLJ10808 stained with Coomassie Blue
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Wheat Germ Extract
GST
68.31 kDa
10 µg/$479; 25 µg/$670
UBE1L2 / UBE1L2 Protein - 12.5% SDS-PAGE of human FLJ10808 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
69.6 kDa
10 µg/$479; 25 µg/$670
UBE1L2 / UBE1L2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
117.8 kDa
100 µg/$494
Viewing 1-6 of 6 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).