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Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.
Gene Name: | U2 small nuclear RNA auxiliary factor 1 |
Synonyms: | U2AF1, FP793, U2AF35, U2AFBP, RNU2AF1, RN |
Target Sequences: | NM_006758 NP_006749.1 Q01081 |
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