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TYRP1 / gp75
tyrosinase-related protein 1
Oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized.
| Gene Name: | tyrosinase-related protein 1 |
| Synonyms: | TYRP1, B-PROTEIN, CAS2, CATB, Glycoprotein 75, Hstyrrp, gp75, OCA3, SHEP11, TRP-1, Tyrosinase-related protein 1, TYRP, TYRRP, Catalase B, DHICA oxidase, Melanoma antigen gp75 |
| Target Sequences: | NM_000550 NP_000541.1 P17643 |
Publications (1)
1
In vitro modeling of hyperpigmentation associated to neurofibromatosis type 1 using melanocytes derived from human embryonic stem cells. Jennifer Allouche, Nathalia Bellon, Manoubia Saidani, Laure Stanchina-Chatrousse, Yolande Masson, Anand Patwardhan, Floriane Gilles-Marsens, Cédric Delevoye, Sophie Domingues, Xavier Nissan, Cécile Martinat, Gilles Lemaitre, Marc Peschanski, Christine Baldeschi. Proceedings of the National Academy of Sciences of the United States of America. 2015 July;112:9034-9. [Full Text Article]
[PubMed:26150484]
[PMC:PMC4517235]
Related Antibodies: LS-B4011.
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Proteins
(5)
Type
Over-Expression Lysate
(2)
Recombinant
(3)
Target
TYRP1 / gp75
(5)
Publications
No
(5)
Tag
GST
(1)
His
(1)
Myc-DDK (Flag)
(3)
Species
Human
(4)
Source
293T Cells
(1)
HEK 293 Cells
(2)
Human Cells
(1)
Wheat Germ Extract
(1)
Purification
Purified
(1)
Low Endotoxin Level
Low endotoxin level
(1)
HEK 293 Cells
Myc-DDK (Flag)
58 kDa
20 µg/$1,107
Wheat Germ Extract
GST
87.1 kDa
10 µg/$479; 25 µg/$670
293T Cells
Myc-DDK (Flag)
60.72 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
60.72 kDa
100 µg/$494
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
52.2 kDa
50 µg/$721
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