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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TXNIP

thioredoxin interacting protein

May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).

Gene Name: thioredoxin interacting protein
Synonyms: TXNIP, HHCPA78, THIF, VDUP1, Thioredoxin binding protein 2, Thioredoxin-binding protein 2, EST01027
Target Sequences: NM_006472 NP_006463.3 Q9H3M7

Filtered by: None
Target
TXNIP (62)
Reactivity
Human (42)
Mouse (30)
Rat (12)
Bat (8)
Bovine (8)
Chimpanzee (9)
Dog (12)
Gibbon (6)
Guinea pig (4)
Monkey (9)
Orangutan (6)
Pig (4)
Rabbit (8)
Sheep (4)
Xenopus (4)
Application
IHC (10)
IHC-P (6)
WB (51)
ELISA (22)
IF (4)
IP (4)
Host
rabbit (60)
mouse (2)
Isotype
IgG (33)
IgG1 (1)
IgG2b (1)
Clonality
monoclonal mc (2)
polyclonal pc (60)
Clone
JY1 (1)
JY2 (1)
Format
AP Conjugated (2)
APC (2)
APC Conjugated (4)
Azide-free (2)
Biotin Conjugated (9)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (9)
HRP Conjugated (9)
PE Conjugated (4)
Unconjugated (21)
Epitope
aa1-30 (8)
aa116-145 (8)
aa30-381 (8)
aa32-367 (8)
C-Terminus (4)
aa121-170 (4)
aa65-114 (4)
N-Terminus (1)
aa100-150 (1)
aa300-350 (1)
Publications
No (62)
Showing 1-25 of 62 results

TXNIP Antibody (C-Terminus) IHC-plus™ LS-B5829
Rabbit Polyclonal (IgG) to Human TXNIP
Xenopus, Bat, Rat, Pig, Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Human, Monkey
IHC IHC-P WB
Unconjugated
100µl 0.5mg/ml  $485.00
Anti-TXNIP antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TXNIP Antibody (C-Terminus, HRP) LS-C455677
Rabbit Polyclonal (IgG) to Human TXNIP
Xenopus, Rat, Bat, Pig, Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Human, Monkey, Gibbon, Chimpanzee, Orangutan
IHC IHC-P WB
HRP Conjugated
100µl 0.65mg/ml  $405.00
Anti-TXNIP antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TXNIP Antibody (C-Terminus, Biotin) LS-C455673
Rabbit Polyclonal (IgG) to Human TXNIP
Xenopus, Rat, Bat, Pig, Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Human, Monkey, Gibbon, Chimpanzee, Orangutan
IHC IHC-P WB
Biotin Conjugated
100µl 1mg/ml  $405.00
Anti-TXNIP antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TXNIP Antibody (C-Terminus, FITC) LS-C455675
Rabbit Polyclonal (IgG) to Human TXNIP
Xenopus, Rat, Bat, Pig, Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Human, Monkey, Gibbon, Chimpanzee, Orangutan
IHC IHC-P WB
FITC Conjugated
100µl 1mg/ml  $405.00
Anti-TXNIP antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TXNIP Antibody (clone JY2) LS-C179729
Mouse Monoclonal [clone JY2] (IgG1) to Human TXNIP
Mouse, Rat, Human
IP WB
Unconjugated
100µg 1mg/ml  $405.00
Western blot Image
Immunoprecipitation Image

TXNIP Antibody (aa116-145) LS-C157966
Rabbit Polyclonal to Mouse TXNIP
Mouse
WB
Unconjugated
400µl  $325.00
Mouse Txnip Antibody western blot of mouse stomach tissue lysates (35 ug/lane). The Mouse Txnip antibody detected the Mouse Txnip protein (arrow).

TXNIP Antibody IHC-plus™ LS-B12126
Rabbit Polyclonal (IgG) to Human TXNIP
Mouse, Rat, Human
ELISA IF IHC IHC-P WB
Unconjugated
0.05mg 1mg/ml  $425.00
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

TXNIP Antibody (aa121-170) LS-C117038
Rabbit Polyclonal to Human TXNIP
Dog, Bovine, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $365.00
TXNIP antibody Western blot of Fetal Lung lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

TXNIP Antibody (aa100-150) LS-C148750
Rabbit Polyclonal to Human TXNIP
Human, Monkey
WB
Unconjugated
100µg 0.5mg/ml  $335.00
Western blot of TxNIP in Raji cell lysate in the 1) absence and 2) presence of immunizing peptide using Polyclonal Antibody to TxNIP at 2 ug/ml. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution were used for this test.

TXNIP Antibody (aa300-350) IHC-plus™ LS-B15082
Rabbit Polyclonal (IgG) to Human TXNIP
Human
IHC IHC-P IP
Unconjugated
50µl 1mg/ml  $425.00
Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)

TXNIP Antibody LS-C661350
Rabbit Polyclonal (IgG) to Human TXNIP
Human
ELISA IF IHC WB
Unconjugated
100µg  $435.00

TXNIP Antibody LS-C410876
Rabbit Polyclonal (IgG) to Human TXNIP
Mouse, Human
IF IHC IP WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00

TXNIP Antibody LS-C671905
Rabbit Polyclonal (IgG) to Human TXNIP
Human
ELISA IF
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunofluorescence staining of MCF-7 cells at a dilution of 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 °C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L) .

TXNIP Antibody LS-C771531
Rabbit Polyclonal (IgG) to Human TXNIP
Mouse, Rat, Human
ELISA IHC
Unconjugated
20µl 1.9mg/ml  $195.00; 60µl 1.9mg/ml  $235.00; 120µl 1.9mg/ml  $285.00; 200µl 1.9mg/ml  $375.00

TXNIP Antibody LS-C771532
Rabbit Polyclonal (IgG) to Human TXNIP
Mouse, Rat, Human
ELISA IHC
Unconjugated
20µl 0.9mg/ml  $195.00; 60µl 0.9mg/ml  $235.00; 120µl 0.9mg/ml  $285.00; 200µl 0.9mg/ml  $375.00

TXNIP Antibody (aa1-30) LS-C326112
Rabbit Polyclonal (IgG) to Human TXNIP
Human
ELISA WB
Unconjugated
200µl  $590.00

TXNIP Antibody (aa1-30, AP) LS-C224552
Rabbit Polyclonal (IgG) to Human TXNIP
Human
ELISA WB
AP Conjugated
200µl  $740.00

TXNIP Antibody (aa1-30, APC) LS-C224554
Rabbit Polyclonal (IgG) to Human TXNIP
Human
ELISA WB
APC Conjugated
200µl  $740.00

TXNIP Antibody (aa116-145, Biotin) LS-C224549
Rabbit Polyclonal (IgG) to Mouse TXNIP
Mouse
ELISA WB
Biotin Conjugated
200µl  $740.00

TXNIP Antibody (aa116-145, FITC) LS-C224550
Rabbit Polyclonal (IgG) to Mouse TXNIP
Mouse
ELISA WB
FITC Conjugated
200µl  $740.00

TXNIP Antibody (aa116-145, AP) LS-C224547
Rabbit Polyclonal (IgG) to Mouse TXNIP
Mouse
ELISA WB
AP Conjugated
200µl  $740.00

TXNIP Antibody (aa116-145, APC) LS-C224548
Rabbit Polyclonal (IgG) to Mouse TXNIP
Mouse
ELISA WB
APC Conjugated
200µl  $740.00

TXNIP Antibody (aa116-145, Azide-free, HRP) LS-C224551
Rabbit Polyclonal (IgG) to Mouse TXNIP
Mouse
ELISA WB
HRP Conjugated, Azide-free
200µl  $740.00

TXNIP Antibody (aa116-145, PE) LS-C224553
Rabbit Polyclonal (IgG) to Mouse TXNIP
Mouse
ELISA WB
PE Conjugated
200µl  $740.00

TXNIP Antibody (clone JY1) LS-C179728
Mouse Monoclonal [clone JY1] (IgG2b) to Human TXNIP
Mouse, Human
IP WB
Unconjugated
100µg 1mg/ml  $380.00
Western blot Image
Immunoprecipitation Image
Showing 1-25 of 62 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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