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Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.
Gene Name: | thioredoxin domain containing 17 |
Synonyms: | TXNDC17, Thioredoxin-like protein 5, TRP14, TXNL5, Thioredoxin-like 5, Protein 42-9-9 |
Target Sequences: | NM_032731 NP_116120.1 Q9BRA2 |
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