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TXNDC12
Thioredoxin Domain Containing 12 (endoplasmic Reticulum)
TXNDC12 is a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants.
| Gene Name: | Thioredoxin Domain Containing 12 (endoplasmic Reticulum) |
| Synonyms: | TXNDC12, AGR1, Anterior gradient homolog 1, ERP18, ERP19, ER protein 19, AG1, HTLP19, PDIA16, TLP19, Thioredoxin-like protein p19, ER protein 18, ERP16, HAG-1 |
| Target Sequences: | NM_015913 NP_056997.1 O95881 |
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