TWIST1 / TWIST

twist family bHLH transcription factor 1

Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the basic domains of both proteins. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion. Activates transcription as a heterodimer with E proteins. Regulates gene expression differentially, depending on dimer composition. Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression. Heterodimerization is also required for osteoblast differentiation. Represses the activity of the circadian transcriptional activator: NPAS2-ARNTL/BMAL1 heterodimer.

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Products

Antibodies (46)

Type

Primary (46)

Target

TWIST1 / TWIST (46)

Reactivity

Human (43)

Mouse (25)

Rat (21)

Bat (3)

Bovine (9)

Chicken (9)

Chimpanzee (9)

Gibbon (3)

Horse (9)

Monkey (9)

Orangutan (9)

Pig (6)

Xenopus (3)

Zebrafish (6)

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Application

IHC (5)

IHC-P (3)

WB (37)

Flo (6)

DB (2)

ELISA (9)

ICC (4)

IF (4)

IP (4)

Peptide-ELISA (1)

RNAi (1)

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Host

rabbit (36)

mouse (7)

sheep (3)

Product Group

IHCPlus (1)

Isotype

F(ab')2 (1)

IgG (22)

IgG1 (4)

IgG1,k (1)

IgG2b (2)

Clonality

monoclonal mc (7)

polyclonal pc (38)

recombinant monoclonal rmc (1)

Clone

10E4E6 (1)

2F8E7 (2)

3E11 (1)

Twist2C1a (2)

Format

APC Conjugated (1)

Biotin Conjugated (4)

CF Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

Preservative Free (1)

Unconjugated (32)

Epitope

N-Terminus (11)

C-Terminus (4)

aa1-159 (2)

Amino Acid: 9-74 (1)

aa1-202 (1)

aa1-50 (1)

aa22-71 (1)

aa9-74 (1)

Publications

No (44)

Yes (2)

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IHC-plus™ TWIST1 / TWIST Antibody (N-Terminus) LS-B6741

(4.0) Rating

Antibody:

TWIST1 / TWIST Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$565

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TWIST1 / TWIST Antibody (C-Terminus) LS-C30601

(4.0) Rating

(1) Publication(s)

Antibody:

TWIST1 / TWIST Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

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TWIST1 / TWIST Antibody (N-Terminus) LS-C352964

Antibody:

TWIST1 / TWIST Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

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TWIST1 / TWIST Antibody (clone Twist2C1a) LS-C342433

Antibody:

TWIST1 / TWIST Mouse anti-Human Monoclonal (Twist2C1a) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

DB, Flo, ICC, IF, WB

Format:

Unconjugated

Price:

100 µg/$486

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TWIST1 / TWIST Antibody LS-C346358

Antibody:

TWIST1 / TWIST Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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TWIST1 / TWIST Antibody LS-C76653

Antibody:

TWIST1 / TWIST Mouse anti-Human Monoclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, Flo, ICC, WB

Format:

Unconjugated

Price:

50 µg/$558

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TWIST1 / TWIST Antibody (aa1-159, APC) LS-C132778

Antibody:

TWIST1 / TWIST Sheep anti-Human Polyclonal (aa1-159) (APC) Antibody

Reactivity:

Human

Applications:

Flo

Format:

APC Conjugated

Price:

100 Tests/$907

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TWIST1 / TWIST Antibody (clone Twist2C1a) LS-C184384

Antibody:

TWIST1 / TWIST Mouse anti-Human Monoclonal (Twist2C1a) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

DB, Flo, ICC, WB

Format:

Unconjugated

Price:

100 µg/$965

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TWIST1 / TWIST Antibody (clone 3E11) LS-C198386

Antibody:

TWIST1 / TWIST Mouse anti-Human Monoclonal (3E11) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, IP, RNAi, WB

Format:

Unconjugated

Price:

100 µg/$423

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TWIST1 / TWIST Antibody (N-Terminus) LS-C153587

Antibody:

TWIST1 / TWIST Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$440; 100 µg/$480

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TWIST1 / TWIST Antibody LS-C416874

Antibody:

TWIST1 / TWIST Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

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TWIST1 / TWIST Antibody LS-C661343

Antibody:

TWIST1 / TWIST Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$351

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TWIST1 / TWIST Antibody (clone 2F8E7) LS-C169139

Antibody:

TWIST1 / TWIST Mouse anti-Human Monoclonal (2F8E7) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$459

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TWIST1 / TWIST Antibody LS-C661341

Antibody:

TWIST1 / TWIST Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

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TWIST1 / TWIST Antibody LS-C780486

Antibody:

TWIST1 / TWIST Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

TWIST1 / TWIST Antibody LS-C836200

Antibody:

TWIST1 / TWIST Rabbit Recombinant Monoclonal Antibody

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

10 µl/$299; 100 µl/$548

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TWIST1 / TWIST Antibody LS-C671301

Antibody:

TWIST1 / TWIST Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

TWIST1 / TWIST Antibody LS-C833501

Antibody:

TWIST1 / TWIST Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

TWIST1 / TWIST Antibody (aa22-71) LS-C200041

Antibody:

TWIST1 / TWIST Rabbit anti-Human Polyclonal (aa22-71) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

TWIST1 / TWIST Antibody LS-C408684

Antibody:

TWIST1 / TWIST Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

TWIST1 / TWIST Antibody LS-C834425

Antibody:

TWIST1 / TWIST Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

TWIST1 / TWIST Antibody (Amino Acid: 9-74, clone 2F8E7) LS-C759723

Antibody:

TWIST1 / TWIST Mouse anti-Human Monoclonal (Amino Acid: 9-74) (2F8E7) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$503

Select

TWIST1 / TWIST Antibody LS-C314086

Antibody:

TWIST1 / TWIST Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$431

Select

TWIST1 / TWIST Antibody LS-C746577

Antibody:

TWIST1 / TWIST Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$434

Select

TWIST1 / TWIST Antibody LS-C771518

Antibody:

TWIST1 / TWIST Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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