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TUT1

terminal uridylyl transferase 1, U6 snRNA-specific

Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs. Localizes to nuclear speckles together with PIP5K1A and mediates polyadenylation of a select set of mRNAs, such as HMOX1. In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs. In addition to adenylyltransferase activity, also has uridylyltransferase activity. However, the ATP ratio is higher than UTP in cells, suggesting that it functions primarily as a poly(A) polymerase. Acts as a specific terminal uridylyltransferase for U6 snRNA in vitro: responsible for a controlled elongation reaction that results in the restoration of the four 3'-terminal UMP-residues found in newly transcribed U6 snRNA. Not involved in replication-dependent histone mRNA degradation.

Gene Name: terminal uridylyl transferase 1, U6 snRNA-specific
Synonyms: TUT1, RNA binding motif protein 21, RNA-binding protein 21, STARPAP, U6 TUTase, U6-TUTase, RBM21, RNA uridylyltransferase, PAPD2, RNA-binding motif protein 21, Star-PAP, TUTase
Target Sequences: NM_022830 NP_073741.2 Q9H6E5

☰ Filters
Antibodies (16)
Proteins (3)
Over-Expression Lysate (2)
Primary (16)
Recombinant (1)
TUT1 (19)
Human (15)
Mouse (4)
Rat (4)
Bat (3)
Bovine (3)
Chimpanzee (9)
Dog (6)
Gibbon (3)
Guinea pig (6)
Horse (3)
Monkey (6)
Orangutan (6)
Pig (6)
IHC (3)
IHC-P (1)
WB (14)
ELISA (2)
Peptide-ELISA (2)
rabbit (16)
IgG (12)
polyclonal pc (16)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (7)
N-Terminus (4)
aa253-302 (4)
aa829-878 (4)
260-340 aa, Internal (1)
aa291-340 (1)
No (19)
Myc-DDK (Flag) (3)
Human (2)
293T Cells (1)
HEK 293 Cells (2)
TUT1 Antibody - TUT1 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TUT1 Rabbit anti-Human Polyclonal (aa253-302) Antibody
Human
WB
Unconjugated
100 µl/$424
TUT1 Antibody - TUT1 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TUT1 Rabbit anti-Human Polyclonal (aa253-302) (HRP) Antibody
Dog, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
TUT1 Antibody - TUT1 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
TUT1 Rabbit anti-Human Polyclonal (aa253-302) (Biotin) Antibody
Dog, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
TUT1 Antibody - TUT1 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
TUT1 Rabbit anti-Human Polyclonal (aa253-302) (FITC) Antibody
Dog, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
Select
TUT1 Rabbit anti-Human Polyclonal (260-340 aa, Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
TUT1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$357
TUT1 Antibody - Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using TUT1 Antibody. The picture on the right is blocked with the synthesized peptide.
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TUT1 Rabbit anti-Human Polyclonal (aa291-340) Antibody
Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
TUT1 Antibody - Western blot analysis of TUTase using 3T3 whole cells lysates
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TUT1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TUT1 Antibody - TUT1 antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
TUT1 Rabbit anti-Human Polyclonal (aa829-878) Antibody
Human
WB
Unconjugated
100 µl/$424
TUT1 Antibody - TUT1 antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
TUT1 Rabbit anti-Human Polyclonal (aa829-878) (HRP) Antibody
Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
TUT1 Antibody - TUT1 antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
TUT1 Rabbit anti-Human Polyclonal (aa829-878) (Biotin) Antibody
Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
TUT1 Antibody - TUT1 antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
TUT1 Rabbit anti-Human Polyclonal (aa829-878) (FITC) Antibody
Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
TUT1 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
TUT1 Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Rat
WB
Unconjugated
100 µl/$424
TUT1 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
TUT1 Rabbit anti-Rat Polyclonal (N-Terminus) (HRP) Antibody
Mouse, Dog, Guinea pig, Rat, Pig, Orangutan, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
TUT1 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
TUT1 Rabbit anti-Rat Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Dog, Guinea pig, Rat, Pig, Orangutan, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
TUT1 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
TUT1 Rabbit anti-Rat Polyclonal (N-Terminus) (FITC) Antibody
Mouse, Dog, Guinea pig, Rat, Pig, Orangutan, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
TUT1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
98.3 kDa
20 µg/$150
TUT1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
98.3 kDa
100 µg/$494
TUT1 Protein - Purified recombinant protein TUT1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
98.3 kDa
20 µg/$1,107
Viewing 1-19 of 19 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).