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TUSC3

tumor suppressor candidate 3

TUSC3 is a candidate tumor suppressor gene. It is located within a homozygously deleted region of a metastatic prostate cancer. The gene is expressed in most nonlymphoid human tissues including prostate, lung, liver, and colon. Expression was also detected in many epithelial tumor cell lines. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene Name: tumor suppressor candidate 3
Synonyms: TUSC3, D8S1992, M33, MRT7, N33, OST3A, Tumor suppressor candidate 3, Protein N33, MRT22
Target Sequences: NM_006765 NP_006756.2 Q13454

Publications (2)

1
Low levels of tumor suppressor candidate 3 predict poor prognosis of patients with hepatocellular carcinoma. Sheng XR, Xing SG, Wang RD, Chen K, Jia WD. OncoTargets and therapy. 2018 February;11:909-917. (Human) [Full Text Article] [PubMed:29503566] [PMC:PMC5825997] Related Antibodies: LS-B13274.
2
miRNA-mediated TUSC3 deficiency enhances UPR and ERAD to promote metastatic potential of NSCLC. Jeon YJ, Kim T, Park D, Nuovo GJ, Rhee S, Joshi P, Lee BK, Jeong J, Suh SS, Grotzke JE, Kim SH, Song J, Sim H, Kim Y, Peng Y, Jeong Y, Garofalo M, Zanesi N, Kim J, Liang G, Nakano I, Cresswell P, Nana-Sinkam P, Cui R, Croce CM. Nature communications. 2018 November;9:5110. [Full Text Article] [PubMed:30504895] [PMC:PMC6269493] Related Antibodies: LS-C384735.

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Products
Antibodies (19)
Primary (19)
TUSC3 (19)
Human (19)
Mouse (8)
Rat (8)
Bat (1)
Bovine (1)
Chicken (1)
Dog (1)
Hamster (1)
Monkey (2)
Rabbit (1)
Xenopus (1)
Zebrafish (1)
IHC (4)
IHC-P (2)
WB (16)
ELISA (6)
ICC (2)
IF (6)
Peptide-ELISA (3)
rabbit (18)
goat (1)
Product Group
IHCPlus (1)
IgG (10)
polyclonal pc (19)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (13)
N-Terminus (4)
100-180 aa, Internal (1)
His153 (1)
Internal (1)
aa131-180 (1)
aa95-106 (1)
No (17)
Yes (2)
TUSC3 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
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TUSC3 Rabbit anti-Human Polyclonal (Internal) Antibody
Bovine, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
TUSC3 Antibody - Western blot of N33 antibody
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TUSC3 Rabbit anti-Human Polyclonal (100-180 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
TUSC3 Antibody - Western blot of COLO205 cell lysate using TUSC3 Antibody
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TUSC3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µg/$305; 100 µg/$357
TUSC3 Antibody - Immunohistochemistry Dilution at 1:300 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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TUSC3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
TUSC3 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
TUSC3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
TUSC3 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
TUSC3 Antibody - Peptide - + Immunofluorescence analysis of HeLa cells, using TUSC3 antibody.
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TUSC3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
TUSC3 Antibody - Immunofluorescence analysis of HeLa cells using TUSC3 Antibody. The picture on the right is blocked with the synthesized peptide.
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TUSC3 Rabbit anti-Human Polyclonal (aa131-180) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
TUSC3 Antibody - Staining COLO205 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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TUSC3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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TUSC3 Rabbit anti-Human Polyclonal (His153) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
TUSC3 Antibody - Antibody (1 ug/ml) staining of Human Liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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TUSC3 Goat anti-Human Polyclonal (aa95-106) Antibody
Xenopus, Chicken, Zebrafish, Rabbit, Mouse, Dog, Bat, Rat, Hamster, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
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TUSC3 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
TUSC3 Antibody - Western blot of TUSC3 Antibody with human U937 Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TUSC3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
TUSC3 Antibody - Western blot of TUSC3 Antibody with human U937 Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TUSC3 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
TUSC3 Antibody - Western blot of TUSC3 Antibody with human U937 Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TUSC3 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
TUSC3 Antibody - Western blot of TUSC3 Antibody with human U937 Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TUSC3 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
TUSC3 Antibody - Western blot analysis of extracts of various cell lines, using TUSC3 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
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TUSC3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
TUSC3 Antibody - Anti-TUSC3 Antibody at 1:1000 dilution + HeLa whole cell lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 40 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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TUSC3 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$386
Viewing 1-19 of 19 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).