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TUBB / Beta Tubulin

tubulin, beta class I

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

Gene Name:	tubulin, beta class I
Synonyms:	TUBB, Beta Tubulin, Beta 5-tubulin, Beta-4 tubulin, Beta1-tubulin, M40, Tubulin beta-5 chain, Beta Ib tubulin, Class I beta-tubulin, OK/SW-cl.56, TUBB5, Tubulin beta chain, Tubulin beta polypeptide, Tubulin beta-1 chain, Tubulin, beta class I, Tubulin, beta polypeptide
Target Sequences:	NM_178014 NP_821133.1 P07437

Publications (8)

The genomic response of the retinal pigment epithelium to light damage and retinal detachment. Rattner A, Toulabi L, Williams J, Yu H, Nathans J. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2008 28:9880-9. [PubMed:18815272] [PMC:PMC2570851]

Akt regulates L-type Ca2+ channel activity by modulating Cavalpha1 protein stability. Catalucci D, Zhang DH, DeSantiago J, Aimond F, Barbara G, Chemin J, Bonci D, Picht E, Rusconi F, Dalton ND, Peterson KL, Richard S, Bers DM, Brown JH, Condorelli G. The Journal of cell biology. 2009 184:923-33. [PubMed:19307602] [PMC:PMC2699149]

THY1 is a conserved marker of undifferentiated spermatogonia in the pre-pubertal bull testis. Reding SC, Stepnoski AL, Cloninger EW, Oatley JM. Reproduction (Cambridge, England). 2010 139:893-903. (WB; Human) [PubMed:20154176]

ADAM15 exerts an antiapoptotic effect on osteoarthritic chondrocytes via up-regulation of the X-linked inhibitor of apoptosis. Bhm B, Hess S, Krause K, Schirner A, Ewald W, Aigner T, Burkhardt H. Arthritis and rheumatism. 2010 62:1372-82. (WB) [PubMed:20213810]

Human immunodeficiency virus type 1 endocytic trafficking through macrophage bridging conduits facilitates spread of infection. Kadiu I, Gendelman HE. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2011 6:658-75. (ICC; Human) [PubMed:21789505] [PMC:PMC3232570]

NEUROG3 is a critical downstream effector for STAT3-regulated differentiation of mammalian stem and progenitor spermatogonia. Kaucher AV, Oatley MJ, Oatley JM. Biology of reproduction. 2012 86:164, 1-11. (WB; Mouse) [PubMed:22378757] [PMC:PMC3364931]

Differences in iNOS and arginase expression and activity in the macrophages of rats are responsible for the resistance against T. gondii infection. Li Z, Zhao ZJ, Zhu XQ, Ren QS, Nie FF, Gao JM, Gao XJ, Yang TB, Zhou WL, Shen JL, Wang Y, Lu FL, Chen XG, Hide G, Ayala FJ, Lun ZR. PloS one. 2012 7:e35834. (WB; Mouse, Rat) [PubMed:22558235] [PMC:PMC3338469]

Increased IFN activity and differential antibody response in patients with a history of Lyme disease and persistent cognitive deficits. Jacek E, Fallon BA, Chandra A, Crow MK, Wormser GP, Alaedini A. Journal of neuroimmunology. 2013 255:85-91. (WB; Mouse) [PubMed:23141748] [PMC:PMC3557545]

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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