TUBA1A / Tubulin Alpha 1a

tubulin, alpha 1a

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

TUBA1A / Tubulin Alpha 1a (6)

Publications

No (6)

Tag

6His, N-terminus (1)

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human TUBA1A / Tubulin Alpha 1a Protein (Recombinant 6His, N-terminus) (Arg2-Tyr451) - LS-G97052

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

~50 kDa (55 kDa reducing conditions)

Price:

10 µg/$265; 100 µg/$365; 50 µg/$315

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Human TUBA1A / Tubulin Alpha 1a Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72677

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50 kDa

Price:

20 µg/$1,107

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Human TUBA1A / Tubulin Alpha 1a Protein (Recombinant GST, N-terminus) (aa352-451) - LS-G60611

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human TUBA1A / Tubulin Alpha 1a Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93257

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50 kDa

Price:

20 µg/$150

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Human TUBA1A / Tubulin Alpha 1a Protein (Recombinant GST) (Full Length) - LS-G31014

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

75.24 kDa

Price:

2 µg/$439

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TUBA1A / Tubulin Alpha 1a Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115595

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50 kDa

Price:

100 µg/$494

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