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TTR / Transthyretin
transthyretin
TTR / Transthyretin is transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.
| Gene Name: | transthyretin |
| Synonyms: | TTR, ATTR, CTS1, CTS, HsT2651, PALB, Prealbumin, TBPA, Transthyretin, Carpal tunnel syndrome 1, Prealbumin, amyloidosis type I, Thyroxine-binding prealbumin |
| Target Sequences: | NM_000371 NP_000362.1 P02766 |
Publications (4)
1
Gene expression and functional annotation of human choroid plexus epithelium failure in Alzheimer's disease. Bergen AA, Kaing S, ten Brink JB; Netherlands Brain Bank, Gorgels TG, Janssen SF. BMC genomics. 2015 16:956. (IHC; Human)
[Full Text Article]
[PubMed:26573292]
[PMC:PMC4647590]
2
A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing. Finn JD, Smith AR, Patel MC, Shaw L, Youniss MR, van Heteren J, Dirstine T, Ciullo C, Lescarbeau R, Seitzer J, Shah RR, Shah A, Ling D, Growe J, Pink M, Rohde E, Wood KM, Salomon WE, Harrington WF, Dombrowski C, Strapps WR, Chang Y, Morrissey DV. Cell reports. 2018 February;22:2227-2235. [Full Text Article]
[PubMed:29490262]
Related Antibodies: LS-C407961.
3
Rare Variants in MME, Encoding Metalloprotease Neprilysin, Are Linked to Late-Onset Autosomal-Dominant Axonal Polyneuropathies. Michaela Auer-Grumbach, Stefan Toegel, Maria Schabhüttl, Daniela Weinmann, Catharina Chiari, David L H Bennett, Christian Beetz, Dennis Klein, Peter M Andersen, Ilka Böhme, Regina Fink-Puches, Michael Gonzalez, Matthew B Harms, William Motley, Mary M Reilly, Wilfried Renner, Sabine Rudnik-Schöneborn, Beate Schlotter-Weigel, Andreas C Themistocleous, Jochen H Weishaupt, Albert C Ludolph, Thomas Wieland, Feifei Tao, Lisa Abreu, Reinhard Windhager, Manuela Zitzelsberger, Tim M Strom, Thomas Walther. American journal of human genetics. 2016 September;99:607-623. [Full Text Article]
[PubMed:27588448]
[PMC:PMC5011077]
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TTR / Transthyretin
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Publications
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(179)
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(1)
TTR / Transthyretin Rabbit anti-Rat Polyclonal (aa21-147) Antibody
Mouse, Rat
IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
TTR / Transthyretin Goat anti-Human Polyclonal (aa89-100) Antibody
Human, Monkey
ELISA, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
TTR / Transthyretin Goat anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
0.25 mg/$485
TTR / Transthyretin Mouse anti-Human Monoclonal (aa21-147) Antibody
Human
ELISA, WB
Unconjugated
50 µl/$525
TTR / Transthyretin Mouse anti-Human Monoclonal (Ready-to-Use) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$338
TTR / Transthyretin Chicken anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
TTR / Transthyretin Rabbit anti-Human Polyclonal (aa71-98) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
TTR / Transthyretin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
TTR / Transthyretin Mouse anti-Human Monoclonal (4D8) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
TTR / Transthyretin Guinea pig anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
TTR / Transthyretin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC-P, WB
Unconjugated
50 µl/$460
TTR / Transthyretin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
TTR / Transthyretin Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse
ELISA, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
TTR / Transthyretin Rabbit anti-Mouse Polyclonal (aa21-147) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
TTR / Transthyretin Rabbit anti-Mouse Polyclonal (aa21-147) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248
TTR / Transthyretin Rabbit anti-Mouse Polyclonal (aa23-147) Antibody
Mouse
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
TTR / Transthyretin Mouse anti-Human Monoclonal (2E10C5) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
TTR / Transthyretin Mouse anti-Human Monoclonal (aa21-147) Antibody
Human
WB
Unconjugated
100 µl/$305; 200 µl/$345; 500 µl/$479; 1 ml/$547; 2 ml/$725; 5 ml/$1,192
TTR / Transthyretin Mouse anti-Human Monoclonal (aa21-147) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$314; 200 µl/$359; 500 µl/$506; 1 ml/$580; 2 ml/$797; 5 ml/$1,295
TTR / Transthyretin Rabbit anti-Guinea pig Polyclonal (aa12-126) Antibody
Guinea pig
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
TTR / Transthyretin Rabbit anti-Human Polyclonal (aa47-74) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
Cancer Pathology
Cancer
Fast Shipping
TTR / Transthyretin Rabbit anti-Human Polyclonal Antibody
IHC-P, SWB
Unconjugated
50 µg/$460
TTR / Transthyretin Rabbit anti-Monkey-Cynomolgus Polyclonal (aa21-147) (HRP) Antibody
Monkey-Cynomolgus
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
TTR / Transthyretin Rabbit anti-Monkey-Cynomolgus Polyclonal (aa21-147) (Biotin) Antibody
Monkey-Cynomolgus
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
TTR / Transthyretin Pig anti-Human Polyclonal Antibody
Human
ID, IHC-P
Unconjugated
0.05 ml/$460
Viewing 26-50
of 180
product results
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