TTN / Titin

Titin

TTN / Titin is a large abundant protein of striated muscle. The product of this gene is divided into two regions, a N-terminal I-band and a C-terminal A-band. The I-band, which is the elastic part of the molecule, contains two regions of tandem immunoglobulin domains on either side of a PEVK region that is rich in proline, glutamate, valine and lysine. The A-band, which is thought to act as a protein-ruler, contains a mixture of immunoglobulin and fibronectin repeats, and possesses kinase activity. An N-terminal Z-disc region and a C-terminal M-line region bind to the Z-line and M-line of the sarcomere, respectively, so that a single titin molecule spans half the length of a sarcomere. Titin also contains binding sites for muscle associated proteins so it serves as an adhesion template for the assembly of contractile machinery in muscle cells. It has also been identified as a structural protein for chromosomes. Alternative splicing of this gene results in multiple transcript variants. Considerable variability exists in the I-band, the M-line and the Z-disc regions of titin. Variability in the I-band region contributes to the differences in elasticity of different titin isoforms and, therefore, to the differences in elasticity of different muscle types. Mutations in this gene are associated with familial hypertrophic cardiomyopathy 9, and autoantibodies to titin are produced in patients with the autoimmune disease scleroderma.

☰ Filters

Products

Antibodies (30)

Type

Primary (30)

Target

TTN / Titin (30)

Reactivity

Human (30)

Mouse (5)

Rat (5)

Chicken (1)

Pig (1)

Rabbit (2)

Application

IHC (9)

IHC-Fr (1)

IHC-P (3)

WB (26)

ELISA (9)

IF (5)

Peptide-ELISA (2)

Host

rabbit (17)

mouse (13)

Isotype

IgG (7)

IgG1 (1)

IgG1,k (1)

IgG2a,k (2)

IgG2b (1)

IgG2b,k (8)

Clonality

monoclonal mc (13)

polyclonal pc (17)

Clone

2B3 (1)

6H5 (1)

7D3 (1)

C1 (8)

T11 (1)

Format

APC (2)

APC Conjugated (2)

Biotin Conjugated (3)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (13)

Epitope

aa33779-34025 (8)

aa161-210 (1)

aa5398-5604 (1)

aa7169-7203 (1)

Publications

No (30)

Select

TTN / Titin Antibody (clone 2B3) LS-C133497

Antibody:

TTN / Titin Mouse anti-Human Monoclonal (2B3) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

TTN / Titin Antibody LS-C39732

Antibody:

TTN / Titin Mouse anti-Human Monoclonal Antibody

Reactivity:

Rabbit, Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

1 ml/$801

Select

TTN / Titin Antibody (clone T11) LS-C92870

Antibody:

TTN / Titin Mouse anti-Chicken Monoclonal (T11) Antibody

Reactivity:

Chicken, Rat, Pig, Rabbit, Human

Applications:

IF, IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

100 µl/$660

Select

TTN / Titin Antibody LS-C808913

Antibody:

TTN / Titin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

TTN / Titin Antibody (aa5398-5604) LS-C285743

Antibody:

TTN / Titin Rabbit anti-Human Polyclonal (aa5398-5604) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

TTN / Titin Antibody (HRP) LS-C316733

Antibody:

TTN / Titin Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

TTN / Titin Antibody (Biotin) LS-C318724

Antibody:

TTN / Titin Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

TTN / Titin Antibody (FITC) LS-C317095

Antibody:

TTN / Titin Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

TTN / Titin Antibody (clone 7D3) LS-C133498

Antibody:

TTN / Titin Mouse anti-Human Monoclonal (7D3) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

TTN / Titin Antibody (clone 6H5) LS-C133499

Antibody:

TTN / Titin Mouse anti-Human Monoclonal (6H5) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

TTN / Titin Antibody (aa161-210) LS-C813947

Antibody:

TTN / Titin Rabbit anti-Human Polyclonal (aa161-210) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

TTN / Titin Antibody (aa7169-7203) LS-C393114

Antibody:

TTN / Titin Rabbit anti-Human Polyclonal (aa7169-7203) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

200 µl/$393

Select

TTN / Titin Antibody LS-C780777

Antibody:

TTN / Titin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC-P

Format:

Unconjugated

Price:

100 µg/$357

Select

TTN / Titin Antibody LS-C833844

Antibody:

TTN / Titin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

TTN / Titin Antibody (clone C1) LS-C663673

Antibody:

TTN / Titin Mouse anti-Human Monoclonal (C1) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$289; 200 µl/$323; 500 µl/$435; 1 ml/$491; 2 ml/$605; 5 ml/$1,045

Select

TTN / Titin Antibody (clone C1, HRP) LS-C710102

Antibody:

TTN / Titin Mouse anti-Human Monoclonal (HRP) (C1) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$313; 200 µl/$356; 500 µl/$502; 1 ml/$575; 2 ml/$785; 5 ml/$1,275

Select

TTN / Titin Antibody (clone C1, Biotin) LS-C686175

Antibody:

TTN / Titin Mouse anti-Human Monoclonal (Biotin) (C1) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$297; 200 µl/$334; 500 µl/$457; 1 ml/$519; 2 ml/$665; 5 ml/$1,120

Select

TTN / Titin Antibody (clone C1, FITC) LS-C692799

Antibody:

TTN / Titin Mouse anti-Human Monoclonal (FITC) (C1) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$320; 200 µl/$367; 500 µl/$524; 1 ml/$605; 2 ml/$835; 5 ml/$1,373

Select

TTN / Titin Antibody (clone C1, Cy3) LS-C701080

Antibody:

TTN / Titin Mouse anti-Human Monoclonal (Cy3) (C1) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$367; 200 µl/$435; 500 µl/$691; 1 ml/$850; 2 ml/$1,096; 5 ml/$1,961

Select

TTN / Titin Antibody (clone C1, PE) LS-C724161

Antibody:

TTN / Titin Mouse anti-Human Monoclonal (PE) (C1) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$367; 200 µl/$435; 500 µl/$691; 1 ml/$850; 2 ml/$1,096; 5 ml/$1,961

Select

TTN / Titin Antibody (clone C1, APC, Cy7) LS-C733155

Antibody:

TTN / Titin Mouse anti-Human Monoclonal (APC, Cy7) (C1) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$446; 200 µl/$547; 500 µl/$978; 1 ml/$1,152; 2 ml/$1,569; 5 ml/$2,941

Select

TTN / Titin Antibody (clone C1, APC) LS-C739891

Antibody:

TTN / Titin Mouse anti-Human Monoclonal (APC) (C1) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$367; 200 µl/$435; 500 µl/$691; 1 ml/$850; 2 ml/$1,096; 5 ml/$1,961

• Unconjugated
• HRP
• Biotin
• FITC
• Cy3
• PE
• APC, Cy7
• More...
  • APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • Cy3
  • PE
  • APC, Cy7
  • APC

Select

TTN / Titin Antibody (aa33779-34025) LS-C296682

Antibody:

TTN / Titin Rabbit anti-Human Polyclonal (aa33779-34025) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182

Select

TTN / Titin Antibody (aa33779-34025, HRP) LS-C710101

Antibody:

TTN / Titin Rabbit anti-Human Polyclonal (aa33779-34025) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$331; 200 µl/$383; 500 µl/$556; 1 ml/$665; 2 ml/$901; 5 ml/$1,511

Select

TTN / Titin Antibody (aa33779-34025, Biotin) LS-C686174

Antibody:

TTN / Titin Rabbit anti-Human Polyclonal (aa33779-34025) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$313; 200 µl/$357; 500 µl/$503; 1 ml/$576; 2 ml/$788; 5 ml/$1,279

• Unconjugated
• HRP
• Biotin

• Unconjugated
• HRP
• Biotin

Viewing 1-25 of 30 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Antibodies

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.