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TTLL5

tubulin tyrosine ligase-like family, member 5

Polyglutamylase which preferentially modifies alpha-tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step (By similarity). Required for CCSAP localization to both spindle and cilia microtubules. Increases the effects of NCOA2 in glucocorticoid receptor-mediated repression and induction and in androgen receptor-mediated induction.

Gene Name:	tubulin tyrosine ligase-like family, member 5
Synonyms:	TTLL5, KIAA0998, STAMP, Tubulin polyglutamylase TTLL5
Target Sequences:	NM_015072 NP_055887.3 Q6EMB2

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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