TTC8

tetratricopeptide repeat domain 8

The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.

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Products

Antibodies (13)

Proteins (5)

Type

Over-Expression Lysate (2)

Primary (13)

Recombinant (3)

Target

TTC8 (18)

Reactivity

Human (13)

Mouse (1)

Rat (1)

Bovine (1)

Chicken (1)

Chimpanzee (3)

Dog (1)

Gibbon (3)

Hamster (4)

Horse (4)

Monkey (4)

Orangutan (3)

Pig (1)

Rabbit (4)

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Application

WB (13)

ELISA (7)

IP (1)

Peptide-ELISA (1)

Host

rabbit (12)

goat (1)

Isotype

IgG (7)

Clonality

polyclonal pc (13)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (5)

Epitope

aa18-46 (7)

aa71-120 (4)

aa316-327 (1)

Publications

No (18)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

Select

TTC8 Antibody LS-C660497

Antibody:

TTC8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

TTC8 Antibody (aa18-46) LS-C326083

Antibody:

TTC8 Rabbit anti-Human Polyclonal (aa18-46) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

TTC8 Antibody (aa18-46, Biotin) LS-C272698

Antibody:

TTC8 Rabbit anti-Human Polyclonal (aa18-46) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

TTC8 Antibody (aa18-46, FITC) LS-C272699

Antibody:

TTC8 Rabbit anti-Human Polyclonal (aa18-46) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

TTC8 Antibody (aa18-46, Azide-free, HRP) LS-C272700

Antibody:

TTC8 Rabbit anti-Human Polyclonal (aa18-46) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

TTC8 Antibody (aa18-46, APC) LS-C272696

Antibody:

TTC8 Rabbit anti-Human Polyclonal (aa18-46) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

TTC8 Antibody (aa18-46, PE) LS-C272703

Antibody:

TTC8 Rabbit anti-Human Polyclonal (aa18-46) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

Select

TTC8 Antibody (aa316-327) LS-C112992

Antibody:

TTC8 Goat anti-Human Polyclonal (aa316-327) Antibody

Reactivity:

Chicken, Bovine, Rat, Hamster, Pig, Horse, Rabbit, Mouse, Dog, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

Select

TTC8 Antibody (aa71-120) LS-C111228

Antibody:

TTC8 Rabbit anti-Human Polyclonal (aa71-120) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

TTC8 Antibody (aa71-120, HRP) LS-C452130

Antibody:

TTC8 Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody

Reactivity:

Rabbit, Hamster, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

TTC8 Antibody (aa71-120, Biotin) LS-C452128

Antibody:

TTC8 Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody

Reactivity:

Rabbit, Hamster, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

TTC8 Antibody (aa71-120, FITC) LS-C452129

Antibody:

TTC8 Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody

Reactivity:

Rabbit, Hamster, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

TTC8 Antibody (aa18-46) LS-C160305

Antibody:

TTC8 Rabbit anti-Human Polyclonal (aa18-46) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

Human TTC8 Protein (Recombinant GST, N-terminus) (aa416-514) - LS-G63608

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human TTC8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83649

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.1 kDa

Price:

20 µg/$150

Select

Human TTC8 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69015

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.1 kDa

Price:

20 µg/$1,107

Select

Human TTC8 Protein (Recombinant GST) (Full Length) - LS-G36338

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

83.7 kDa

Price:

2 µg/$439

Select

TTC8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G103778

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.1 kDa

Price:

100 µg/$494

Viewing 1-18 of 18 product results

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