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TTBK2

tau tubulin kinase 2

Serine/threonine kinase that acts as a key regulator of ciliogenesis: controls the initiation of ciliogenesis by binding to the distal end of the basal body and promoting the removal of CCP110, which caps the mother centriole, leading to the recruitment of IFT proteins, which build the ciliary axoneme. Has some substrate preference for proteins that are already phosphorylated on a Tyr residue at the +2 position relative to the phosphorylation site. Able to phosphorylate tau on serines in vitro.

Gene Name: tau tubulin kinase 2
Family/Subfamily: Protein Kinase , TTBK
Synonyms: TTBK2, KIAA0847, SCA11, Tau-tubulin kinase 2, TTBK, Tau tubulin kinase 2, Spinocerebellar ataxia 11
Target Sequences: NM_173500 NP_775771.3 Q6IQ55

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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
TTBK2 (4)
No (4)
GST (1)
His-GST (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
TTBK2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
137.2 kDa
20 µg/$150
TTBK2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
137.2 kDa
100 µg/$494
TTBK2 Protein - Recombinant Tau-Tubulin Kinase 2 By SDS-PAGE
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E. coli
His-GST
63.7 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
TTBK2 Protein - 12.5% SDS-PAGE of human TTBK2 stained with Coomassie Blue
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Wheat Germ Extract
GST
80.4 kDa
2 µg/$439
Viewing 1-4 of 4 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).