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TSPO / PBR

translocator protein (18kDa)

Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein.

Gene Name: translocator protein (18kDa)
Synonyms: TSPO, BZRP, BPBS, IBP, MBR, MDRC, PBR, PBRS, PBS, PKBS, PTBR, Pk18, Translocator protein, Translocator protein (18kDa)
Target Sequences: NM_000714 NP_000705.2 P30536

Publications (3)

1
SPECT imaging of glioma with radioiodinated CLINDE: evidence from a mouse GL26 glioma model. Tsartsalis S, Dumas N, Tournier BB, Pham T, Moulin-Sallanon M, Grégoire MC, Charnay Y, Millet P. EJNMMI research. 2015 5:9. (WB; Mouse) [Full Text Article] [PubMed:25853015] [PMC:PMC4385259] Related Antibodies: LS-B5755.
2
TSPO activation modulates the effects of high pressure in a rat ex vivo glaucoma model. Makoto Ishikawa, Takeshi Yoshitomi, Douglas F Covey, Charles F Zorumski, Yukitoshi Izumi. Neuropharmacology. 2016 December;111:142-159. [Full Text Article] [PubMed:27596950] [PMC:PMC5473616]
3
Neuroinflammation trajectories precede cognitive impairment after experimental meningitis-evidence from an in vivo PET study. Vijayasree V Giridharan, Allan Collodel, Jaqueline S Generoso, Giselli Scaini, Rico Wassather, Sudhakar Selvaraj, Rodrigo Hasbun, Felipe Dal-Pizzol, Fabricia Petronilho, Tatiana Barichello. Journal of neuroinflammation. 2020 Jan;17:5. [Full Text Article] [PubMed:31901235] [PMC:PMC6942362] Related Antibodies: LS-B14234.

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Products
ELISA Kits (8)
Custom (3)
Sandwich (5)
TSPO / PBR (8)
Human (2)
Mouse (2)
Rat (2)
Pig (1)
96-Well Microplate (1)
96-Well Strip Plate (7)
No (8)
Cell Culture Supernatants (1)
Cell Lysates (2)
Plasma (3)
Serum (3)
Tissue Homogenates (3)
TSPO / PBR ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
TSPO / PBR ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
TSPO / PBR ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
TSPO / PBR ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$834
TSPO / PBR ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$646
TSPO / PBR ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$783
TSPO / PBR ELISA Kit
Select
Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$783
TSPO / PBR ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).