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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TSHB / TSH-Beta

thyroid stimulating hormone, beta

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.

Gene Name: thyroid stimulating hormone, beta
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: TSHB, Thyrotropin alfa, Thyrotropin beta subunit, TSH Beta, TSH-B, Thyrotropin beta chain, Thyrotropin subunit beta, TSH-BETA, CHNG4
Target Sequences: NM_000549 NP_000540.2 P01222

Publications (1)

1
MicroRNAs regulate pituitary development, and microRNA 26b specifically targets lymphoid enhancer factor 1 (Lef-1), which modulates pituitary transcription factor 1 (Pit-1) expression. Zhang Z, Florez S, Gutierrez-Hartmann A, Martin JF, Amendt BA. The Journal of biological chemistry. 2010 285:34718-28. (IHC-P; Mouse) [PubMed:20807761] [PMC:PMC2966087] Related Antibodies: LS-C42182.

Viewing 1-12 of 12 items
TSHB / TSH-Beta Protein
Select
E. coli
His
20µg   0.25mg/ml   $315.00; 100µg   0.25mg/ml   $695.00
Select
E. coli
6His,N-terminus
14.7 kDa
10µg   $275.00; 50µg   $455.00; 100µg   $605.00; 200µg   $875.00; 1mg   $2,265.00; 500µg   $1,005.00
TSHB / TSH-Beta Protein - Recombinant  Thyroid Stimulating Hormone Beta By SDS-PAGE
Select
E. coli
His + GST + S
43.7 kDa
10µg   $285.00; 50µg   $485.00; 100µg   $665.00; 200µg   $965.00; 1mg   $2,475.00; 500µg   $1,095.00
TSHB / TSH-Beta Protein
Select
E. coli
His + SUMO
28.89 kD
1mg   $1,290.00; 500µg   $830.00; 200µg   $485.00; 50µg   $275.00; 10µg   $245.00; 100µg   $355.00
TSHB / TSH-Beta Protein - Purified recombinant protein TSHB was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc + DDK
13.5 kDa
20µg   $890.00
TSHB / TSH-Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc + DDK
15.61 kDa
20µg   $195.00
Select
E. coli
His
2µg   $195.00; 10µg   $255.00; 100µg   $1,260.00
TSHB / TSH-Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc + DDK
15.61 kDa
100µg   $365.00
TSHB / TSH-Beta Protein - Recombinant Thyroid Stimulating Hormone Beta (TSHb) by SDS-PAGE
Select
E. coli
His, N-Terminal
Less than 1.0 EU/µg protein (determined by LAL method).
18.7kDa
10µg   $265.00; 50µg   $415.00; 200µg   $755.00; 100µg   $605.00; 1mg   $2,265.00; 500µg   $1,005.00
Select
None
Biologically active
15 kDa
10µg   $475.00
TSHB / TSH-Beta Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Yeast
6His,N-terminus + Myc,C-terminus
16.4 kDa
1mg   $2,205.00; 500µg   $1,425.00; 200µg   $860.00; 100µg   $515.00; 50µg   $365.00; 10µg   $305.00
TSHB / TSH-Beta Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
10His,N-terminus + Myc,C-terminus
19.9 kDa
1mg   $1,845.00; 500µg   $1,185.00; 200µg   $710.00; 100µg   $445.00; 50µg   $325.00; 10µg   $275.00

Viewing 1-12 of 12 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).