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TSC22D1 / TSC22
TSC22 domain family, member 1
TSC22D1 / TSC22 is a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
| Gene Name: | TSC22 domain family, member 1 |
| Synonyms: | TSC22D1, Cerebral protein 2, Ptg-2, Regulatory protein TSC-22, TSC22 domain family protein 1, TGFB1I4, TSC22, TSC22 domain family, member 1, KIAA1994, TGFbeta-stimulated clone 22 |
| Target Sequences: | NM_006022 NP_006013.1 Q15714 |
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